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Basic unit of the nervouse system.
Chemicals synthesized in nerve cells that are released when stimulated.
Chemical structure on the surface of a cell where certain molecules attach to produce an effect.
Compound that binds to a specific receptor and produces a biological effect by stimulating the receptor.
A drug that prevents natural substances from stimulating receptors by combining with the receptor but producing no effect.
Excitatory neurotransmitters of the CNS
Inhibitory neurotransmitters of the CNS
Neurotransmitters of the PNS
Level of stimulus needed to produce a painful sensation
Similar in most people
Amount of pain a person can endure without it interfering with normal function
Sensation of pain
Indications for Morphine
- Mod-Severe pain
- Medullary Cough
Side effects of Morphine
- Lowers seizure threshold
- Respiratory Depression
- Rash, Itching
- GI upset
- Urinary retention
What do yu treat a morphine OD with?
Contraindications with Morphine
Use caution with geriatrics because they metabolize meds slower
Indications for acetaminophen
What is the mechanism of action for Acetaminophen?
Interferes with prostaglandin and prevents synthesis
Contraindications with acetaminophen
Very harmful to liver because that is where it is metabolized. Should not consume with alcohol
Indications for NSAIDs
Side Effects of NSAIDs
- GI upset because of prostaglandin
- Renal impairment
Symptoms of OD with NSAIDs
- Electrolyte imbalance
Considerations with NSAIDs and Children
Do not give to children <16. Could cause Reye's Syndrome
What drug treats seizure disorders?
Side effects of Dilantin
- Gingival hyperplasia
- Slurred speech
Which drug has a narrow therapeutic index of 10-20mcg/mL
Nursing considerations for Dilantin
- Teach good oral hygeine
- Watch for bleeding/bruising
What would you like to do?
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