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How is total vascular resistance changed
Vasocontriction modulation from sympathetic NS
Types of local control of blood flow
- Basal tone - nerve independent vessel tone
- Blood flow autoregulation - constant flow despite perfusion pressure
- Active/Functional Hyperemia
- Reactive Hyperemia
What are the theories of autoregulation?
Myogenic - autoregulation is intrinsic to vessel (stretched vessels contract to compensate)
Metabolic - Vasodilator metabolites are produced by the tissue
Higher blood flow seen when functional activity increased
Blood flow increased after period of restricted blood flow
- Norepinephrine, epinephrine
- Angiotension II
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