17 Adaptive

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Author:
pkellyle
ID:
80442
Filename:
17 Adaptive
Updated:
2011-04-18 17:19:41
Tags:
micro
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Description:
Specific defense
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  1. Four major function of Antibody IgG
    • 1. Passive immunity - mother to fetus
    • 2. Neutralize bacteria - with toxin
    • 3. trigger complement
    • 4. enhances phagocytosis
  2. 5 major func of IgA - dimer mucous membrane
    • 1. prevent attachment of pathogen to mucous membrane
    • 2. combat respiratory pathogens
    • 3. protect infants from gastrointernal infections
    • 4. protect genitourinary system
    • 5. activates complement
  3. Func of IgM
    • 1. response to ABO blood grouping antigens
    • 2. Enhances phagocytosis
    • 3. Promote antigen aggregation - binding, activate complement.
    • 4. 1st produced antibody
  4. Func. of IgE in allergic response
    • 1. When binding to antigen, it causes mast cells or basophils to release histamines.
    • * response to parasitic worm infection (increased # of anitbody)
    • *found primarily in body fluids and skin
  5. What is the difference between active immunity and passive immunity?
    • * Passive is premade antibdies get from hospitals or mother.
    • * active is when you get sick and your body produce anitbodies against the specific antigen
  6. What is the difference between antigen, epitope, haptens and antibodies?
    • * Antigen - is a protein or subunit part of a pathogen that sparks an adaptive immune response
    • * Epitopes (antigenic determinants) - are the specific sites on an antigen reacts with. THERE ARE MANY in ONE ANTIGEN
    • * Hapten - too small to be antigens, needs to bind to a carrier.
    • *antibodies - protein, also called (Immunoglobulins - Ig)

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