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Four major function of Antibody IgG
- 1. Passive immunity - mother to fetus
- 2. Neutralize bacteria - with toxin
- 3. trigger complement
- 4. enhances phagocytosis
5 major func of IgA - dimer mucous membrane
- 1. prevent attachment of pathogen to mucous membrane
- 2. combat respiratory pathogens
- 3. protect infants from gastrointernal infections
- 4. protect genitourinary system
- 5. activates complement
Func of IgM
- 1. response to ABO blood grouping antigens
- 2. Enhances phagocytosis
- 3. Promote antigen aggregation - binding, activate complement.
- 4. 1st produced antibody
Func. of IgE in allergic response
- 1. When binding to antigen, it causes mast cells or basophils to release histamines.
- * response to parasitic worm infection (increased # of anitbody)
- *found primarily in body fluids and skin
What is the difference between active immunity and passive immunity?
- * Passive is premade antibdies get from hospitals or mother.
- * active is when you get sick and your body produce anitbodies against the specific antigen
What is the difference between antigen, epitope, haptens and antibodies?
- * Antigen - is a protein or subunit part of a pathogen that sparks an adaptive immune response
- * Epitopes (antigenic determinants) - are the specific sites on an antigen reacts with. THERE ARE MANY in ONE ANTIGEN
- * Hapten - too small to be antigens, needs to bind to a carrier.
- *antibodies - protein, also called (Immunoglobulins - Ig)