Card Set Information
Standard antipsychotic drugs are also called
Dopamine Receptor Antagonists
What is an example of a low potency neuroleptic and why is it used less frequently than high potency?
Low-potency neuroleptics such as chlorpromazine (
) are used less frequently than high-potency neuroleptic medications because of problems with orthostatic hypotension.
What are 2 high potency neuroleptics?
** high-potency drugs have less sedation and fewer anticholinergic effects, they cause more EPS than low-potency agents.
What is Neuroleptic Malignant Syndrome?
Severe muscle rigidity with confusion, agitation, increased temperature, pulse, and blood pressure suggest a serious condition—
Atypical Antipsychotic Drugs are aka
serotonin-dopamine antagonists (SDAs)
Clozapine (SDA) is relatively free of motor side effects
is indicated for severely ill schizophrenic individuals who have failed to respond to standard therapy.
Clozapine is not used as a first-line treatment because it may suppress bone marrow
The Blocking of dopamine reduces
the positive symptoms of schitzophrenia
Positive Symptoms of Schitzophrenia
¡Hallucinations-distortion of perceptions
¡Delusions-distortion of thought content
¡Grossly disorganized or catatonic behaviors
Negative symptoms of Schitzophrenia
¡Apathy (suppression of emotions)
¡Alogia (inablility to speak)
¡Lack of motivation
¡Blunted /flat affect (failure to express feelings)
¡Loss of emotional warmth
¡Impaired social skills
(-) symptoms are treated with ?
(+) symptoms are treated with ?
(-) a typical antipsychotics
(+) Hospitalization, Atypical antipsychotics and typical antipsychotics, Reduced stimuli, Interactive therapy
What are the major side effects of Typical Antipsychotics?
Major Side Effects: dopamine blockage (EPS), noradrenergic (Alpha 1)blockage, cholinergic blockage
What are some atypical antipsychotic examples?
What is the tx for NMS?
¡Dantrolene- antidote for hyperthermia
¡Dopaminergics -Bromocriptine, amantadine
Risperidol has a high risk of
weight gain, sedation