Which two adrenal glucocorticoids (GC) are produced in response to signals from the pituitary (ACTH) and hypothalamus (CRH)?
cortisol and corticosterone
Adrenal produces 2 other major hormone types
1)androgens (mainly DHEA) which are also produced in response to ACTH and
2)MC (aldosterone and deoxycorticosterone) which are regulated mainly by Ang II and K+
1)GC are used to:
2)MC are used to:
1)suppress immune function and inflammation
2)treat adrenal insufficiency
All adrenal steroids are derived from
Stress stimulates release of CRH (hypothal) which stimulates release of ACTH (pituitary) which stimlulates release of GC (adrenal). What provides negative feedback to CRH and ACTH?