Bone Mineral Homeostasis

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  1. Parathyroid hormone release is increased when serum calcium levels are increased or decreased?
    Decreased
  2. Calcitonin levels are increased when serum calcium levels are increased or decreased?
    Increased
  3. Which answer is NOT correct:
    Calcitriol is:
    A. increased by PTH action in the kidney
    B. also known as 25-OH-vitamin D3
    C. obtained through diet
    D. synthesized from cholesterol
    B. It is also known as 1,25 (OH)2 -Vitamin D3
    (this multiple choice question has been scrambled)
  4. Which is true:
    a. 7-dehydrocholesterol is converted to cholecalciferol (vitamin D3) by UV light in the skin
    b. Vitamin D3 is converted in the liver to 25-OH-D3 (calcifediol)
    c. 25-OH-D3 is converted in the kidney to 1,25(OH)2D3 (calcitriol)
    d. All of the above
    e. None of the above
    d.
  5. Calcitriol does NOT act by:
    A. Increasing release of Ca10(PO4)6(OH)2 from bone
    B. Increasing reabsorption of calcium in the proximal tubules in the kidney
    C. Increasing calcium absorption in the GI tract
    D. Increasing filtration of calcium from the proximal tubules in the kidney
    D.
    (this multiple choice question has been scrambled)
  6. Calcitonin does not act on the following location:
    A. Bone
    B. GI tract
    C. Proximal tubules
    B.
    (this multiple choice question has been scrambled)
  7. Which of the following causes of osteoporosis is NOT correct:
    A. decreasing dietary calcium
    B. decreasing estrogen
    C. decreasing PTH
    D. physical factors (bone remodeling)
    C. increasing PTH causes bone demineralization
    (this multiple choice question has been scrambled)
  8. Osteoporosis can occur in the following populations:
    a. elderly men
    b. postmenopausal women
    c. people taking glucocorticoids
    d. All of the above
    d.
  9. The main target for osteoporosis treatment is on:
    A. Kidney reabsorption
    B. Kidney filtration
    C. Bone
    D. GI tract
    C.
    (this multiple choice question has been scrambled)
  10. Osteoporosis can be treated with all of the following EXCEPT:
    A. Estrogen
    B. PTH as high, frequent doses
    C. bisphosphonates (alendronate, risedronate, ibandronate)
    D. calcitonin (nasal spray)
    E. Raloxifene (SERMs)
    B. can be treated with PTH as low, intermittent doses
    (this multiple choice question has been scrambled)
  11. Hypocalcemia can be caused by the following EXCEPT:
    A. can be caused by hyperparathyroidism
    B. Vitamin D deficiency
    C. malabsorption states
    D. psuedohypoparathyroidism
    A. can by caused by hypoparathyroidism. causes a decrease in PTH and an increase in phosphate
    (this multiple choice question has been scrambled)
  12. Treatment of hypocalcemia can theoretically be targeted to the following locations EXCEPT:
    a. Bone
    b. Filtration (proximal tubules) in the kidney
    c. Reabsorption (proximal tubules) in the kidney
    d. GI tract
    e. None of the above
    e. All can theoretically be targets for treatment
  13. Calcium supplements which are given orally include all of the following EXCEPT:
    A. Ca gluconate
    B. Ca phosphate
    C. CaCl2
    D. Ca carbonate
    C. This is only given IV because it is very irritating to the GI tract
    (this multiple choice question has been scrambled)
  14. T or F: Vit D supplement as given along side of calcium supplements to treat hypocalcemia.
    T. They help the absorption of Ca
  15. Which of the following statement concerning hypercalcemia is false:
    A. Can be caused by hypoparathyroidism
    B. Can be caused by increased production or ingestion of Vit. D
    C. Can result in CaPO4 deposits in kidney
    D. Malignant neoplasms can be a source of excess Ca
    A. caused by hyperparathyroidism- tumors or hyperplasia of glands
    (this multiple choice question has been scrambled)
  16. Which of the following methods are NOT used to treat hypercalcemia:
    A. bisphosphonates (pamidronate and etidronate)
    B. Saline to increase fluid intake
    C. Oral phosphates and prednisone
    D. Furosemide (diuretics)
    E. PTH
    E. Could use calcitonin to decrease bone resorption instead
    (this multiple choice question has been scrambled)
Author
ID
80848
Card Set
Bone Mineral Homeostasis
Description
Agents that Affect Bone Mineral Homeostasis- Dr. Kasson
Updated
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