ondansetron_hcl.txt

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Author:
papeirce
ID:
80855
Filename:
ondansetron_hcl.txt
Updated:
2011-04-20 12:14:55
Tags:
paramedic medications drugs prehospital ondansetron hcl zofran
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Description:
Prehospital Medication Flashcards for Paramedic School - Massachusetts and Rhode Island
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  1. Ondansetron HCL

    Trade Name
    Zofran
  2. Ondansetron HCL

    Class
    Antiemetic
  3. Ondansetron HCL

    Mechanism of Action
    Selective 5-HT3 receptor antagonist, blocking serotonin, both peripherally on vagal nerve terminals and centrally in the chemoreceptor trigger zone
  4. Ondansetron HCL

    Indications
    Use Prevention of nausea and vomiting
  5. Ondansetron HCL

    Contraindications
    Hypersensitivity
  6. Ondansetron HCL

    Adverse Reactions
    • Malaise/fatigue
    • Headache
    • Drowsiness
    • Fever
    • Dizziness
    • Anxiety
    • Cold Sensation
    • Pruitis
    • Rash
    • Constipation
    • Diarrhea
    • Urinary Retention
    • Injection site reaction
    • Parastesia
    • Hypoxia
  7. Ondansetron HCL

    Drug Interactions
    • Potentiates sedative effects of phenothiaxines
    • CNS depressant may potentiate effects of morphine
    • MAOIs may cause paradoxical excitation
  8. Ondansetron HCL

    How Supplied
    Injection, solution, as hydrochloride (Zofran): 2 mg/mL (2 mL, 20 mL)
  9. Ondansetron HCL

    Dosage and Administration
    Adult
    4 mg. IV
  10. Ondansetron HCL

    Dosage and Administration
    Pediatric
    • Child under or up to 30 kg. 1 mg. IV
    • Child over 30 kg., 2 mg. IV
  11. Ondansetron HCL

    Duration of Action
    • Onset of action: ~30 minutes
    • Half-life elimination:
    • -Children <5 years: 2-3 hours
    • -Adults: 3-6 hours
  12. Ondansetron HCL

    Special Considerations
    Pregnancy safety: Category B

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