diphenhydramine.txt

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Author:
papeirce
ID:
80860
Filename:
diphenhydramine.txt
Updated:
2011-04-20 12:55:48
Tags:
paramedic medications drugs prehospital diphenhydramine benadryl
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Description:
Prehospital Medication Flashcards for Paramedic School - Massachusetts and Rhode Island
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  1. Diphenhydramine

    Trade Name
    Benadryl
  2. Diphenhydramine

    Class
    • Antihistamine
    • Anticholinergic
  3. Diphenhydramine

    Mechanism of Action
    • Blocks cellular histamine receptors
    • Decreases vasodilation
    • Decreases motion sickness
    • Reverses extrapyramidal reactions
  4. Diphenhydramine

    Indications
    • Symptomatic relief of allergies
    • Allergic reactions
    • Anaphylaxis
    • Acute dystonic reactions (phenothiazines).
    • Blood administration reactions
    • Motion sickness
    • Hay fever
  5. Diphenhydramine

    Contraindications
    • Asthma
    • Glaucoma/Narrow Angle Glaucoma
    • Pregnancy
    • Hypertension
    • Infants
    • Patients taking Monoamine Oxidase Inhibitors
  6. Diphenhydramine

    Adverse Reactions
    • Sedation
    • Hypotension
    • Seizures
    • Visual disturbances
    • Vomiting
    • Urinary retention
    • Palpitations
    • Dysrhythmias
    • Dry mouth and throat
    • Paradoxical CNS excitation in children
  7. Diphenhydramine

    Drug Interactions
    • Potentiates effects of alcohol and other anticholinergics
    • May inhibit corticosteroid activity
    • MAOIs prolong anticholinergic effects of diphenhydramine
  8. Diphenhydramine

    How Supplied
    • Tablet: 25, 50 mg
    • Capsules: 25, 50 mg
    • 50 or 100 mg prefilled syringes or vials (IV or IM)
    • 12.5 mg/5 ml elixir
  9. Diphenhydramine

    Dosage and Administration
    Adult
    25 -50 mg IM or IV or P.O.
  10. Diphenhydramine

    Dosage and Administration
    Pediatric
    • 1-2 mg/kg IV, IO slowly or IM
    • If given PO: 5 mg./kg./ 24 hours
  11. Diphenhydramine

    Duration of Action
    • Onset: 15-30 minutes
    • Peak effect: 1 hour
    • Duration: 3-12 hours
  12. Diphenhydramine

    Special Considerations
    • Pregnancy safety: Category B
    • Not used in infants or in pregnancy (Category B).
    • If used in anaphylaxis, will be in conjunction with epinephrine, steroids.

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