Pain meds

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Author:
cdubb777
ID:
81105
Filename:
Pain meds
Updated:
2011-04-23 20:19:39
Tags:
analgesics
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Description:
Opiods/analgesics
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  1. Which plant is morphine from?
    Opium poppy.

    (Papaver somniferum and P album.)
  2. Which is the major analgesic opiod receptor?
    mu
  3. Which drug is a full agonist at the (mu)-opioid
    receptor?
    Morphine.
  4. Which drug is a full antagonist at the (mu)-opioid
    receptor?
    Naloxone.
  5. What are the 3 major classes of opiod receptors?
    mu, delta, kappa
  6. What are some of the effects on the CNS by mu-agonist opioids?
    analgesia, euphoria, sedation, respiratory depression, N/V
  7. Define tolerance of a drug.
    loss of effectiveness
  8. Define physical dependence of a drug.
    • Characteristic withdrawal or abstinence syndrome when
    • a drug is stopped or an antagonist is administered
  9. Are opioid analgesics good for treating chronic pain?
    No, but very effective for acute.
  10. What can opioid agonists do to the GI system? eyes? MSK? heart? kidneys?
    • GUT: slow GI transit, N/V
    • EYES: miosis (constriction)
    • MSK: truncal rigidity (which decreases respiration)
    • heart: bradycardia, hypotension in times of stress
    • Kidneys: decreased, from lower renal flow
  11. What can opioids do to the uterus?
    Prolongs labor...
  12. What's the best way to administer an opioid med?
    • fixed-interval administration (ie, a regular
    • dose at a scheduled time)
  13. What's the brand name of morphine?
    MSContin, Kadian
  14. What's the brand name of oxycodone?
    Oxycontin.
  15. IV morphine is effective for what lung condition?
    dyspnea from pulmonary edema associated with left ventricular heart failure
  16. Which narcotic is reported to have the most pronounced anti-shivering properties?
    • meperidine
    • (though all opioid agonists have some propensity to reduce shivering)
  17. What has been the most successful opioid in transdermal
    application?
    Fentanyl
  18. What is the brand name for Naloxone?
    Narcan.
  19. What are some withdrawl symptoms from opioids?
    • rhinorrhea, lacrimation, yawning, chills, gooseflesh (piloerection), hyperventilation, hyperthermia, mydriasis,
    • muscular aches, vomiting, diarrhea, anxiety, and hostility
  20. What drug is used to treat coma from opioid overdose?
    Narcan (Naloxone)
  21. What are 3 strong agonists (generic name)?
    Morphine, hydromorphone, and oxymorphone
  22. What are 3 strong agonists (brand name)?
    MSContin, Dilaudid, Opana
  23. What is the brand name of hydromorphone?
    Dilaudid
  24. What is the brand name of oxymorphone?
    Opana.
  25. Which opioid is used to relieve difficult-to-treat pain (neuropathic, cancer pain), especially w/ failure of morphine?
    Methadone.
  26. Which opioid can have a negative inotropic action on the heart
    Meperidine.
  27. Codeine,oxycodone, dihydrocodeine, and hydrocodone --> strong agonists, partial agonists or antagonists?
    Partial agonists so weaker than morphine & its derivatives.
  28. What is the generic name of Ultram?
    Tramadol
  29. When IV Narcan is given, how fast does it reverse the opioid effects?
    1-3 minutes.
  30. Norco is combo of which 2 drugs?
    hydrocodone and acetaminophen
  31. Percocet is a combo of which 2 drugs?
    oxycodone and acetaminophen
  32. Darvocet is a combo of which 2 drugs?
    Propoxyphene and acetaminophen
  33. Vicodin is a combo of which 2 drugs?
    hydrocodone and acetaminophen
  34. Name 3 drugs with hydrocodone and acetaminophen? Rank them in terms of amount of acetaminophen.
    Lortab, Norco and Vicodin.

    • Norco: 5/325, 7.5/325, 10/325
    • Lortab: 5/500, 7.5/500, 10/500
    • Vicodin: 5/500, 7.5/750, 10/660
  35. How many mg of codeine does Tylenol #2 have?
    15 mg
  36. How many mg of codeine does Tylenol #3 have?
    30 mg
  37. How many mg of codeine does Tylenol #4 have?
    60 mg
  38. Which drugs are used for dull, poorly localized (visceral pain?)
    Morphine and its derivatives.
  39. Which drugs are used for somatic pain?
    Codeine and its derivatives.
  40. What's the brand name for Meperidine?
    Demerol.
  41. What's the connection between narcotics and histamine?
    They can cause histamine release.
  42. What's the dosing for morphine?
    10 mg/ 70 kg weight
  43. What's the brand name for Methadone?
    Dolophine.

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