323 Transdermal Drug Delivery

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Author:
jgiantess
ID:
81342
Filename:
323 Transdermal Drug Delivery
Updated:
2011-04-23 23:13:01
Tags:
biophysical pharmaceutics
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Description:
prep
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  1. ethanol
    cosolvent
  2. glycerin = glycerol
    cosolvent, adjust to isotonicity
  3. propylene glycol
    cosolvent
  4. PEG 300/400
    cosolvent
  5. polysorbate
    surfactant, wetting agent (non-ionic)
  6. Cremophor-EL
    surfactant, wetting agent (non-ionic)
  7. Pluronics
    surfactant, wetting agent (non-ionic)
  8. lecithin
    surfactant, wetting agent (naturally occurring)
  9. sodium carboxymethylcellulose
    flocculating/suspending agent
  10. methylcellulose
    flocculating/suspending agent
  11. polyvinylpyrrolidone
    flocculating/suspending agent
  12. high MW Polyethylene glycol (PEG 4000, 3350)
    flocculating/suspending agent
  13. citric acid/citrate
    buffer
  14. acetic acid/acetate
    buffer
  15. phosphate
    buffer
  16. benzoic acid/benzoate
    buffer
  17. ascorbic acid
    antioxidants/chelators
  18. bisulfites/metabisulfites
    antioxidants/chelators
  19. EDTA
    antioxidants/chelators
  20. citric acid
    antioxidants/chelators
  21. mannitol
    bulking agent for lyophilization
  22. lactose
    bulking agent for lyophilization
  23. benzalkonium chloride
    preservative
  24. benzyl alcohol
    preservative
  25. parabens
    preservative
  26. chlorobutanol
    preservative
  27. chlorocresol
    preservative
  28. phenol
    preservative
  29. thiomerosal
    preservative
  30. NaCl
    adjust to isotonicity
  31. dextrose
    adjust to isotonicity

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