HPRS Exam 5

Card Set Information

Author:
cotypatricia
ID:
81746
Filename:
HPRS Exam 5
Updated:
2011-04-25 16:24:04
Tags:
Pharmacology Review
Folders:

Description:
DM; Endocrine; Hormone; OP; GERD; PUD
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user cotypatricia on FreezingBlue Flashcards. What would you like to do?


  1. Aspart

    MOA: Mimincs spikes of physiologic secretion of insulin after eating (post prandial)
    Bolus Insulin

    Rapid-acting
  2. Lispro

    MOA: Mimincs spikes of physiologic secretion of insulin after eating (post prandial)
    Bolus Insulin

    Rapid-acting
  3. Glulisine

    MOA: Mimincs spikes of physiologic secretion of insulin after eating (post prandial)
    Bolus Insulin

    Rapid-acting
  4. Regular Insulin

    MOA: Mimincs spikes of physiologic secretion of insulin after eating (post prandial)
    Bolus Insulin

    Short-acting
  5. NPH (neutral protamine hagedorn)

    MOA: Mimics normal pancreatic insuling secretion with constant levels
    Basal Insulin

    Intermediate-acting
  6. Detemir

    MOA: Mimics normal pancreatic insuling secretion with constant levels
    Basal Insulin

    Long-acting
  7. Glargine

    MOA: Mimics normal pancreatic insuling secretion with constant levels
    Basal Insulin

    Long-acting
  8. Diabeta

    MOA: stimulates pancreatic secretion of insulin from Beta cells
    glyburide

    Sulfonylureas - 2nd Generation
  9. Glucotrol

    MOA: stimulates pancreatic secretion of insulin from Beta cells
    glipizide

    Sulfonylureas - 2nd generation
  10. Amaryl

    MOA: stimulates pancreatic secretion of insulin from Beta cells
    glimepiride

    Sulfonylureas - 2nd generation
  11. Orinase

    MOA: stimulates pancreatic secretion of insulin from Beta cells
    tolbutamide

    Sulfonyreas - 1st generation
  12. Diabinese

    MOA: stimulates pancreatic secretion of insulin from Beta cells
    chlorpropamide

    Sulfonyreas - 1st generation
  13. Glucophage

    MOA:
    1) increases insulin receptor sensitivity in muscle and adipose tissue
    2) inhibits hepatic gluconeogenesis
    metformin

    Biguanide
  14. Actos

    MOA:
    1) increases insulin sensitivity
    2) decreases hepatic gluconeogenesis
    pioglitizone

    Glitizone = Thiazolidinediones
  15. Avandia

    MOA:
    1) increases insulin sensitivity
    2) decreases hepatic gluconeogenesis
    rosiglitizone

    Glitizzone - Thiazolidinediones
  16. Precose

    MOA:
    1) inhibits enzyme in small intestine
    2) prevents hydrolysis of sucrose & complex CHOs (carbs)
    3) delays glucose absorption
    4) lowers postprandial hyperglycemia
    acarbose

    Alpha-glucosidase Inhibitor
  17. Glyset

    MOA:1) inhibits enzyme in small intestine2) prevents hydrolysis of sucrose & complex CHOs (carbs)3) delays glucose absorption4) lowers postprandial hyperglycemia
    miglitol

    Alpha-glucosidase Inhibitor
  18. Prandin

    MOA: stimulates insuling release from pancreatic Beta cells
    repaglinide

    Meglitinides
  19. Starlix

    MOA: stimulates insuling release from pancreatic Beta cells
    nateglinide

    Meglitinides
  20. Symlin

    MOA:
    1) acts as analog for amylin
    2) secreted with insulin by beta cells
    3) reduces postprandial glucose increases (hyperglycemia)
    pramlintide

    Amylin Analogs
  21. Januvia

    MOA:
    1) Inhibit DPP-4 enzyme
    2) prolongs active GLP-1 & GIP secretion levels from incretin system
    sitagliptin

    Dipeptidyl Peptidase-4 (DPP-4) Inhibitors
  22. Onlyza

    MOA:1) Inhibit DPP-4 enzyme2) prolongs active GLP-1 & GIP secretion levels from incretin system
    saxagliptin

    Dipeptidyl Peptidase-4 (DPP-4) Inhibitors
  23. Byetta

    MOA:
    1) Acts as analog of GLP-1 hormone
    2) increases Beta cell growth & replication
    3) increases insulin secretion
    4) slows gastric emptying
    5) may decrease food intake
    exenatide

    GLP-1 agonist
  24. Victoza

    MOA:
    1) Acts as analog of GLP-1 hormone
    2) increases Beta cell growth & replication
    3) increases insulin secretion
    4) slows gastric emptying
    5) may decrease food intake
    liraglutide

    GLP-1 agonist
  25. Cortisol

    MOA:
    1) reduces inflammation
    2) Immunosuppression
    3) wide spread effect in body
    hydrocortisone - adrenocoticosteroids

    Natural Glucocoticoid
  26. Prednisone

    MOA:
    1) reduces inflammation
    2) Immunosuppression
    3) wide spread effect in body
    • adrenocoticosteroids
    • Synthetic Glucocorticoid
  27. Methylprednisone

    MOA:
    1) reduces inflammation
    2) Immunosuppression
    3) wide spread effect in body
    adrenocoticosteroids

    Synthetic Glucocorticoid
  28. Triamcinolone

    MOA:
    1) reduces inflammation
    2) Immunosuppression
    3) wide spread effect in body
    adrenocoticosteroids

    Synthetic Glucocorticoid
  29. Dexamethasone

    MOA:1) reduces inflammation2) Immunosuppression3) wide spread effect in body
    adrenocoticosteroids

    Synthetic Glucocorticoid
  30. Aldosterone

    MOA:
    1) promostes reabsorption of Na
    2) promotes excretion of K & H
    3) Tx for orthostatic hypotension & Addison's Disease
    • adrenocoticosteroids
    • Natural Mineralcorticoids
  31. Fludrocortisone

    MOA:1) promostes reabsorption of Na2) promotes excretion of K & H3) Tx for orthostatic hypotension & Addison's Disease
    adrenocoticosteroids

    Synthetic Mineralcorticoid
  32. Propylthiouracil

    MOA:
    1) blocks hormone synthesis
    2) blocks conversion of T4 to T3
    *preferred in women breast feeding
    (PTU)

    Anti-thyroid Agent
  33. Tapazole

    MOA: only blocks hormone synthesis
    * dosed once qd
    methimazole (MMI)

    Anti-thyroid Agent
  34. Synthroid

    MOA: Synthetic T4
    levothyroxine

    Supplimental Thyroid Hormone
  35. Levothroid

    MOA: synthetic T4
    levothyroxine

    Supplimental Thyroid Hormone
  36. Levoxyl

    MOA: synthetic T4
    levothyroxine

    Supplimental Thyroid Hormone
  37. Unithroid

    MOA: synthetic T4
    levothyroxine

    Supplimental Thyroid Hormone
  38. Amour Thyroid

    MOA: disiccated beef or pork thyroid gland
    thyroid USP

    Supplimental Thyroid Hormone
  39. Cytomel

    MOA: synthetic T3
    liothyronine

    Supplimental Thyroid Hormone
  40. Thyrolar

    MOA: synthetic T4:T3 (4:1 ratio)
    liotnix

    Supplimental Thyroid Hormone
  41. Ethinyl Estrodial

    MOA:
    1) supresses FSH release
    2) blocks LH surge
    3) prevents ovulation
    4) stabalizes endometrial lining
    5) provides cycle control
    estrogen

    sex hormone & h0ormone therapy drug (Estrodial)
  42. Mestranol

    MOA: 1) supresses FSH release2) blocks LH surge3) prevents ovulation4) stabalizes endometrial lining5) provides cycle control
    estrogen

    sex hormone
  43. Desogestrel

    MOA:
    1) prevents sperm penetration by thickening cervical mucus
    2) delays sperm transport by slowing tubal motility
    3) prevents ovulation by blocking LH surge
    *provides MOST of the contraceptive effect
    progestin

    sex hormone
  44. Drospirenone

    MOA:
    1) prevents sperm penetration by thickening cervical mucus
    2) delays sperm transport by slowing tubal motility
    3) prevents ovulation by blocking LH surge
    *provides MOST of the contraceptive effect
    progestin

    sex hormone
  45. Norgestimate

    MOA:
    1) prevents sperm penetration by thickening cervical mucus
    2) delays sperm transport by slowing tubal motility
    3) prevents ovulation by blocking LH surge
    *provides MOST of the contraceptive effect
    progestin

    sex hormone
  46. Norethindrone

    MOA:
    1) prevents sperm penetration by thickening cervical mucus
    2) delays sperm transport by slowing tubal motility
    3) prevents ovulation by blocking LH surge
    *provides MOST of the contraceptive effect
    progestin

    sex hormone
  47. Cyclessa

    MOA: contraceptive results with less adrenergic effects (hirsutism & acne)
    desogestrel (progestin)-containing

    contraceptive
  48. Ortho Cept

    MOA: contraceptive results with less adrenergic effects (hirsutism & acne)
    desogestrel (progestin)-containing

    contraceptive
  49. Mircette

    MOA: contraceptive results with less adrenergic effects (hirsutism & acne)
    desogestrel (progestin)-containing

    contraceptive
  50. Desigen

    MOA: contraceptive results with less adrenergic effects (hirsutism & acne)
    desogestrel (progestin)-containing

    contraceptive
  51. Yasmin

    MOA:
    1) antimineralocorticoid acts as progestin components
    2) potassium-sparing (diuretic) effect
    3) decrease in bloating & water retention
    drospirenone (progestin)-containing

    contraceptive
  52. Yaz

    MOA:
    1) antimineralocorticoid acts as progestin components
    2) potassium-sparing (diuretic) effect
    3) decrease in bloating & water retention
    drospirenone (progestin)-containing

    contraceptive
  53. Femcon Fe

    MOA:
    1) contains ethinyl estrodial & norethindrone
    2) can be swallowed or chewed
    3) take with 8 oz water
    estrogen & progestin

    chewable contraceptive
  54. Ortho Evra

    MOA:
    apply one patch (buttock, upper arm/torso, abdomen) once a week for 3 weeks - off for one week
    transdermal contraceptive patch
  55. Progesterone

    MOA: prevent endometrial hyperplasia or cancer
    hormone drug therapy
  56. Black Cohosh

    MOA: complimentary medicine that helps with night sweats
    herbal suppliment

    complimentary hormone therapy
  57. Serophene

    MOA:
    1) stimulates the release of FSH & LH from anterior pituitary gland
    2) binds to estrogen receptors
    3) signals to hypothalmus that estrogen levels are low
    4) stimulates secretion of FSH & LH
    Clomid

    Infertility Drug Therapy
  58. Calcium carbonate

    MOA: highest concentration - possible constipation
    calcium

    OP drug therapy
  59. Vitamin D

    MOA: maximizes intestinal Calcium absorption
    OP drug therapy
  60. alendronate

    MOA:
    1) bind to hydroxyapatite in bone
    2) inhibits osteoclasts
    3) decrease resorption
    Bisphosphonate

    1st line OP drug therapy
  61. risedronte

    MOA:
    1) bind to hydroxyapatite in bone
    2) inhibits osteoclasts
    3) decrease resorption
    Bisphosphonate

    1st line OP drug therapy
  62. Ibandronate

    MOA:
    1) bind to hydroxyapatite in bone
    2) inhibits osteoclasts
    3) decrease resorption
    IV & PO Bisphosphonate

    1st line OP drug therapy
  63. Zoledronic Acid

    MOA:
    1) bind to hydroxyapatite in bone
    2) inhibits osteoclasts
    3) decrease resorption
    IV (only) Bisphosphonate

    1st line OP drug therapy
  64. Evista

    MOA:
    1) Agonist at bone
    2) Antagonist at breast & uterus
    3) acts like estrogen to prevent bone loss
    raloxifen

    "Selective Estrogen Receptor Modulator" - OP drug therapy
  65. Fortical

    MOA:
    1) antagonizes the effects of parathyroid gland
    2) inhibits osteoclast bone resorption
    calcitonin

    OP drug therapy
  66. Miacalcin

    MOA:
    1) antagonizes the effects of parathyroid gland
    2) inhibits osteoclast bone resorption
    calcitonin

    nasal OP drug therapy
  67. Forteo

    MOA:
    1) increases osteoblasts number & activity
    2) increases bone remodling rate
    3) increases bone formation
    teriparatide

    OP drug therapy
  68. Prolia

    MOA:
    1) inhibits RANKL
    2) decreases survival rate of osteoclasts
    3) inhibits bone formation & function
    4) decreased bone resorption
    5) increase bone mass & strength
    denosumab

    RANKL inhibitor - OP drug therapy
  69. Magnesium

    MOA: neutralizes gastric activity
    - causes diarrhea
    antacid

    GERD drug therapy
  70. Caclium

    MOA: neutralizes gastric activity
    - causes constipation
    antacid

    GERD drug therapy
  71. Aluminum HO

    MOA: neutralizes gastric activity
    - causes diarrhea
    antacid

    GERD drug therapy
  72. Sodium Bicarbonate

    MOA: neutralizes gastric activity
    - causes constipation
    antacid

    GERD drug therapy
  73. Cimetidine

    MOA:
    1) inhibit histamine/H2 receptor interaction
    2) decrease secretion of acid & pepsin
    H2 receptor antagonist/blocker

    GERD drug therapy
  74. Famotidine

    MOA:
    1) inhibit histamine/H2 receptor interaction
    2) decrease secretion of acid & pepsin
    H2 receptor antagonist/blocker

    GERD drug therapy
  75. Nizatidine

    MOA:
    1) inhibit histamine/H2 receptor interaction
    2) decrease secretion of acid & pepsin
    H2 receptor antagonist/blocker

    GERD drug therapy
  76. Ranitidine

    MOA:
    1) inhibit histamine/H2 receptor interaction
    2) decrease secretion of acid & pepsin
    H2 receptor antagonist/blocker

    GERD drug therapy
  77. Omeprazolone

    MOA:
    1) inhibition of H/K ATP
    2) blocks gastric acid secretion
    3) prolonged & long lasting antisecretory effects
    Protonm Pump inhibitor

    GERD drug therapy
  78. esomeprazole

    MOA:
    1) inhibition of H/K ATP
    2) blocks gastric acid secretion
    3) prolonged & long lasting antisecretory effects
    Protonm Pump inhibitor

    GERD drug therapy
  79. lansoprazole

    MOA:
    1) inhibition of H/K ATP
    2) blocks gastric acid secretion
    3) prolonged & long lasting antisecretory effects
    Protonm Pump inhibitor

    GERD drug therapy
  80. pantoprazole

    MOA:
    1) inhibition of H/K ATP
    2) blocks gastric acid secretion
    3) prolonged & long lasting antisecretory effects
    Protonm Pump inhibitor

    GERD drug therapy
  81. rabeprazole

    MOA:
    1) inhibition of H/K ATP
    2) blocks gastric acid secretion
    3) prolonged & long lasting antisecretory effects
    Protonm Pump inhibitor

    GERD drug therapy
  82. dexlansoprazole

    MOA:
    1) inhibition of H/K ATP
    2) blocks gastric acid secretion
    3) prolonged & long lasting antisecretory effects
    Protonm Pump inhibitor

    GERD drug therapy
  83. Reglan

    MOA:
    1) enhances the action pof endogenous Ach
    2) stimulates contraction of the LES
    3) reduces daytime heartburn sxs best
    metoclopramide

    dopamine antagonists - GERD drug therapy
  84. Carafate

    MOA: forms a protective barrier over damaged gastric mucosa
    sucralfate

    Mucosal protectants - PUD drug therapy
  85. Misoprostol

    MOA:
    1) analog od prostaglandins
    2) stimulate recpetors in gastric mucosa
    3) mediate bicarbonate production & sedretion of mucous
    4) create protective environement for the stomache
    *uterine contractions - may cause miscarriage
    cytotec

    Prostaglandin Aanalog - PUD drug therapy

What would you like to do?

Home > Flashcards > Print Preview