Chemotherapeutic agents pharmacologic classification

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pdnguyen
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81748
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Chemotherapeutic agents pharmacologic classification
Updated:
2011-04-25 16:27:19
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Chemotherapeutic agents pharmacologic classification
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Chemotherapeutic agents pharmacologic classification
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  1. 6-mercaptopurine
    • Inhibit purine ring biosynthesis
    • Inhibit nucelotide interconversions
  2. PALA
    Inhibits pyrimidine biosynthesis
  3. Hydroxyurea
    Inhibits ribonucleotide reductase
  4. Methotrexate
    Inhibits dihydrofolate reduction, blocks TMP and purine synthesis
  5. Gemcitabine
    Inhibit DNA synthesis
  6. Cytarabine
    Inhibit DNA synthesis
  7. Fludarabine
    Inhibit DNA synthesis
  8. 2-Chlorodeoxyadenosine
    Inhibit DNA synthesis
  9. Camptothecins
    Block topoisomerase function
  10. Etoposide
    Block topoisomerase function
  11. Teniposide
    Block topoisomerase function
  12. Daunorubicin
    Block topoisomerase function
  13. Doxorubicin
    Block topoisomerase function
  14. Protein tyrosine
    Block activity of enzymes
  15. Kinase inhibitors
    Block activity of enzymes
  16. Bortezomib
    Block activity of enzymes
  17. Antibodies
    Block activity of enzymes
  18. Platinum analogs
    Form adducts with DNA
  19. Alkylating agents
    Form adducts with DNA
  20. Mitomycin
    Form adducts with DNA
  21. Cisplatin
    Form adducts with DNA
  22. Temozolomide
    Form adducts with DNA
  23. L-asparaginase
    • Deaminates asparagine
    • Inhibits protein synthesis
  24. Paclitaxel
    Inhibit function of microbubles
  25. Vinca alkaloids
    Inhibit function of microbubles
  26. Colchicine
    Inhibit function of microbubles
  27. Estramustine
    Inhibit function of microbubles
  28. 6-thioguanine
    Inhibit purine ring biosynthesisInhibit nucelotide interconversions

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