Tox 2b

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Author:
mayabug
ID:
81853
Filename:
Tox 2b
Updated:
2011-04-26 01:18:30
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Tox
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Tox
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  1. Mycotoxin
    • moldy feed does not confirm mycotoxicosis
    • do not rule out non-moldy feed bc toxin may have been produced and fungi died
  2. Mycetismus
    • mushroom toxicity- amanita, psilocybe
    • alaloid, muscarine
    • hepatic, reanl, PS, GI, neuro
    • tx patient, not mushroom
    • empty stomach, activated charcoal, atropine
  3. Aflatoxin
    • aspergillus, penicillium
    • B, G, M1
    • dog
    • liver
    • ddx: anticoag rodenticide, algae, cycad, mushroom
    • fish>poultry>K9>Bov>sheep
  4. Ocratoxin
    • aspergillus, penicillium
    • kidney
    • swine
    • grapes
  5. Zearalenone
    • Fusarium
    • prolonged estrus, vulvovaginitis
    • female swine
  6. Tricothecene Mycotoxin
    • Fusarium
    • inhibits protein synthesis
    • Dermatonecrosis, bone marrow dyscrasia, stimulate CRTZ (swine)
    • poultry less sensitive
  7. Tremorgenic toxins
    • aspergillus, penicillium
    • tremortin A, penitrem A
    • walnuts, pecans, cream cheese
    • neuro
    • canine
    • diazepam
  8. Slaframine
    • slobber factor
    • alkaloid
    • salivation
    • bovine, equine
    • prevent with atropine
  9. Equine Leukoencephalomalacia (ELEM)
    • fusonisin
    • carcinogenic
    • liquifactive necrosis of white matter
    • swine- pulm edema
    • do not feed corn screenings
  10. Cyanophyta- Blue green algae
    • anatoxin (alkaloid)- natural OP
    • neuro, GI, liver, skin, renal
  11. snake venom
    • many fractions
    • neurotoxin- Mojave
    • thrombocytopenia
    • early transportation and tx
  12. crotalus, sistrurus
    • rattlesnake
    • Mojave most toxic
  13. agkistrodon
    • copperhead
    • water moccasin
    • can bite while swimming
  14. micrurus, microuroides
    • coral snake
    • red and yellow, kill a fellow
    • red and black, ok Jack
  15. heloderma
    • Gila monster
    • non-aggressive
    • neuro
  16. Bufo Toad
    • cardio active glycosides
    • diazepam, propranolol, atropine
  17. Eurytelenna
    • tarantula
    • painful bite
  18. latrodectus
    • black widow
    • painful bite
    • ascending paralysis
    • (large, swollen areas are not spider bites)
    • antivenin, atropine, robaxin, methocarbamol, 10% Ca gluconate
  19. loxosceles
    • brown recluse
    • non-painful bite
    • non-healing wound
    • dapsone, hyperbaric O2, SQ dex at wound
  20. centruroides
    • scorpions
    • neurotoxic
    • atropine, sedation, proranolol
    • EP contraindicated
  21. sea turtle, polar bear, bearded seal, walrus
    toxin in liver
  22. halogenated organic comp.
    • repro effects
    • esp. birds
    • residue in food
  23. chlorinated naphthalenes
    • blocks carotene to vit A
    • hyperkeratosis (like vetch)
  24. poly-chlorinated biphenyls (PCB)
    • chloracne
    • porphoria
  25. poly-bromated bibphenyls (PBB)
    • chlorachne
    • porphoria
  26. Dioxins
    • 2, 4, 5-T
    • ball clay
    • teratogenic
  27. hexa-chloro-benzene
    • interfere with phorphorin metabolism
    • liver
  28. hexa-chlorophene
    • uncouples ox phosphorylation
    • status spongiosis
    • control fever, enema, diazepam
  29. trichloro-ethylene extracted soybean oil meal (TCESOM)
    • aplastic anemia
    • bone marrow dyscrasia
    • cattle
    • ddx: bracken fern
  30. pneumoconiosis
    • fibrinogenic change in lungs due to inhaled irritans
    • emphysema, fibrogenic response
    • clubbing of fingers
  31. methyliso-cynate (MIC)
    • develop Ab
    • severe pulm irritation
    • edema
  32. polytetra-fluoroethylen (PTFE)
    • Teflon
    • rapid death
    • small birds very sensistive
  33. aflotoxin effects
    • aspergillus
    • liver
    • coagulopathy
  34. ergot effects
    • claviceps
    • vasoconstriction
    • gangrenous extremities
  35. fumonison
    • fusarium
    • neuro
  36. ocratoxin
    • aspergillus, penicillium
    • nephrotoxic
  37. slaframine
    • rhizoctonia
    • histaminic
    • cholinergic
    • salivation
    • lacrymation
  38. T2 toxin
    • fusarium
    • dermonecrosis
    • coagulopathy
  39. zearalenone
    • fusarium
    • estrogens

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