Pharmacology Final

Card Set Information

Author:
Rx2013
ID:
81934
Filename:
Pharmacology Final
Updated:
2011-04-26 12:07:37
Tags:
Glucocorticoids
Folders:

Description:
Glucocorticoids 2
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user Rx2013 on FreezingBlue Flashcards. What would you like to do?


  1. Uses for methylprednisolone
    • ocular inflammation
    • otitis externa
    • inflammatory musculoskeletal conditions
    • ulcerative colitis
    • nephrosis
  2. ADEs with methylprednisolone
    • fluid and e- imbalance
    • sodium retention
    • HTN
    • potassium loss/alkalosis
    • Increases in ALT and AST
  3. Drug interactions with methylprednisolone
    • Drugs that induce hepatic enzymes
    • Phenobarb
    • Phenytoin
    • Rifampin
    • Ketoconazole
    • Troleandomycin
  4. Triamcinolone indication
    • adrenal cortex insufficiency
    • inflammatory disorders
    • allergic disorders
    • connective tissue disorders
  5. Mechanism of action for triamcinolone
    reduces inflammation by modifying the body's immune response
  6. May decrease effectiveness of triamcinolone
    • Inducers of cyp enzymes
    • barbiturates
    • carbamazepine
    • phenytoin
    • rifampin
  7. Severe ADEs with triamcinolone
    • severe allergic reaction
    • black tarry stool
    • changes in menstrual periods
  8. Common ADEs with triamcinolone
    • bone fractures
    • change in appetite
    • change in mood
  9. Ketoconazole Indications
    • Systemic infections in pt who have not responded to topical therapy or oral griseofulvin.
    • candidiasis
    • oral thrush
    • candiduria
  10. Ketoconazole mechanism of action
    adrenal steroid inhibitor
  11. Ketoconazole should not be used for
    fungal meningitis because it penetrates poorly into the CSF
  12. ADEs with ketoconazole
    • photophobia
    • diarrhea
    • gynecomastia
  13. Ketoconazole drug interactions
    potent inhibitor of CYP 3A4
  14. Mitotane indications
    inoperable adrenal cortical carcinoma
  15. Mitotane ADEs
    • Anorexia
    • n/v
    • diarrhea (80% of pt)
  16. 40% of pt on mitotane experience
    CNS ADEs
  17. 15% of pt on mitotane experience
    skin toxicity
  18. 25% of pt on mitotane experience
    somnolence
  19. 15% of pt on mitotane experience (CNS effect)
    Dizziness or vertigo
  20. Drug interactions with mitotane
    accelerates metabolism of warfarin

What would you like to do?

Home > Flashcards > Print Preview