what are the antibiotic allergic reactions important to dental personnel? 10
azo and non azo dyes used in _____, parabens-preservatives used in ____ and sulfites used in ____ are causes fo rallergic reactions important to the dental personnel
what are the five functions of the immune system?
processing of antigens
cellular recognition of antigens
cellular repsonse to presentation of antigen
celluar action against antigen
eradication of antigen
what is a foreign substance that triggers hypersensitivity reactions; cause an immunologic reaction resulting in allergic diseases
what are the 5 types of immunoglobulins?
what immunoglobulin is the most abundant, diffuses into tissues, can cross the placenta, facilitates pagocytosis by neutrophils, binds to mast cells and has four subclass..1,2,3,4
what immunoglobulin is found in saliva, tears, nasal mucous and protects from proteolysis and serum, does not cross placenta and is the last immunoglobulin to appear in childhood?
what immunoglobulin is a large molecule, confined to intravascular sapce, is the first immunoglobulind produced and is a good agglutinating antibody
what immunotglobulin is very low in concentration, increased in parastic and atopic disease, binds to mast cells and basophils and is KETY ANTIBODY IN PATHOGENESIS of TYPE I hyerpsensitivity reactions
what immunoglobulin is low in concentration and little importance?
what type of hypersensitivity is realted to humoral system, mediated by IgE, immediate response.
what type of hypersensitivity usual allergens are dust, mites, pollens, animal dander, foods and drugs
what hypersensitivity is it when symptoms on occasion include anaphylaxis, hay fever, asthma, urticaria and angioedema
hwat % or the popluation is affected by type I hypersensitivity?
what hypersensitivity is mediated by IgG and IgM antibodies and is a Cytotoxic hypersensitivity and the antibodies combine with host cells to recognized as a foreign antigen which binds to host cell membranes during induced hemolytic anemia or thrombocytopenia
what are some examples of type II hypersensitivity?
transfusion reactions from mismatched blood, rhesus incompatibility, good pasture's syndrome
what type of hypersensitivity involves cellular immune system, mediated by T lymphocytes but doesn't involve antibodies
what type of hypersensitivity is the delayed type?
what are some examples of type IV hypersensitivity?
contact dermatitis, graft and transplant rejection, graft vs host reaction, drug hypersensitivity, autoimmune diseases, tuberculin skin test, poison ivy
urticaria, swelling, skin rash, chest tightness, dyspnea, shortness of breath, rhinorrhea, conjunctivitis are all signs and symptoms of what?
_____ allergy examples are syncope after LA injection, nausea or vomiting after ingestion of codeine
talkativenss, slurred speech, dizzienss, nausea, depression, euphoria, excitement, convulsions are all signs and symptoms of what?
toxic reaction to LA
toxic reactions to LA usually result from what?
inadvertent intravenous injection of LA solution..ASPIRATE BABY!
tachycardia, apprehension sweating and hyperactivity are all signs and symptoms of what?
hyperventilation, vasovagal syncope (bardycardia, pallor, sweating) sympathetic stimulation (anxiety, tremor, tachycardia, hypertension) are all signs of what?
psychomotor response to LA injection
what is the LA associated with the highest incidence of allergic reaction?
when should a pt be referred to an allergist?
pt has had allergic reaction to LA but not sure what ingredient triggered allergy
what test is done by the allergist?
provocative dose testing (PDT)
what ROA is contraindicated for penicillins?
what is the preferred ROA for penicillins?
what ROA of penicillins can cuase more serious reactions?
what should pts allergic to penicillin be given for oral infections?
what should be given to pts allergic to penicillins for prophylaxist against infective endocarditis?
what are drugs to avoid for pneicillin allergy? 4
what shoudl not be used for pt with ulcers, gastritis, hemorrhagic disease (prolong prothrombin time/platelet function) or hiatal hernia?
what can provoke severe reactions in asthmatics?
rubber gloves, rubber dam, blood pressure cuff and catheters often cause what type of reaction?
handsoaps used by healthcare workers cause what type of reaction?
dnetal amalgam, acrylic, composite resin, nickel, eugenol, rubber products, talcum powder, mouthwases and toothpastes can all cause what type of reaction?
type IV (contact stomatitis)
uticarial swellings or angioneurotic edema are oral manifesations for what type of reaction?
what is given for a type I reaction?
white erythematous or ulcerative lesions are oral manifestations what type of reaction?
contact stomatitis is an oral manifestation of what type of reaction?
a pt is in the chair and angioneutoric edema is noticed in the tongue, pharyngeal tissues or larynx what type of reaction is the pt having and what should be done?
place in supine
_____ occurs within minutes effecting both the respiratory and circulatory sytem together and is fatal if not taken care of immediately
itching of soft palate, nausea, vomiting, substernal pressure, shortness of breath, hyptension, pruritus, urticaria, laryngeal edema, bronchospasm, cardiac arrhythmias are all signs and symptoms of what?
what is the first thing to be done with an anaphylaxis pt?