Pharm Final II, Psychotropics

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HLW
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82915
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Pharm Final II, Psychotropics
Updated:
2011-05-02 10:10:43
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Pharm
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Pharm Final II, Psychotropics
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  1. Basis for selection of psychotropic drugs (5):
    • Availability
    • General Behavioral Actions
    • Side Fx
    • Reported Therapeutic Fx
    • Neurochemistry
  2. FDA approved psychotropics (3)
    • Clomipramine
    • Fluoxetine
    • Selegiline
  3. Which FDA approved drugs are used to tx separation anxiety in dogs (2)? What do they act on?
    • Clomipramine (Serotonin & Norepi)
    • Fluoxetine (Serotonin)
  4. What FDA Approved drug is used to treat canine cognitive dysfunction? What does it act on?
    Selegiline, MOAf
  5. What areas of the brain does serotonin act on & what are the effects (4)?
    • Limbic Areas- anxiety & panic
    • Basal Ganglia- compulsive disorder
    • Frontal Cortex- mood
    • Neurons of the brainstem- sleep
  6. General effects of Serotonin (3):
    • Anti-Anxiety
    • Anti-compulsive
    • Behavioral calming effect
  7. Fx & Side Fx of Acepromazine in...
    Dogs (3):
    Cats (2):
    • Dogs:
    • Useful in some cases
    • Traquilizer
    • No anti-anxiety
    • Cats:
    • Traquilizer
    • No anti-anxiety
  8. Fx & Side Fx of Diazapam in...
    Dogs: (2)
    Cats: (2)
    • Dogs:
    • Rapid Metab
    • May release inhibition
    • Cats:
    • Sedation
    • Hepatic Necrosis
  9. Fx & Side Fx of Busperone (Buspar) in...
    Dogs (2):
    Cats (2):
    • Dogs:
    • Mild GIT Fx
    • Social Behavior Changes
    • Cats:
    • Mild GIT Fx
    • Social Behavior Changes
  10. Fx & Side Fx of Amitryptyline(Elavil) in...
    Dogs (3):
    Cats (2):
    • Dogs:
    • Mild Sedation
    • GI Fx
    • Anti-Cholinesterase
    • Cats:
    • Mild Sedation
    • Anti-Cholinesterase
  11. Fx & Side Fx Paroxetine (Paxil) in...
    Dogs(2):
    Cats(2):
    • Dogs:
    • Anti-cholinesterase
    • Restlessness
    • Cats:
    • Anti-cholinesterase
    • Restlessness
  12. Fx & Side Fx of Clomipramine (clomicalm) in...
    Dogs(2):
    Cats(2):
    • Dogs:
    • Mild Sedation
    • Vomiting on an empty stomoch
    • Cats:
    • Mild Sedation
    • Vomiting on an empty stomach
  13. Fx & Side Fx of Fluoxetine (Prozac) in...
    Dogs:
    Cats (2):
    • Dogs:
    • Cats:
    • Anti-Choliesterase
    • Sleepiness
  14. Phenothiazines :
    Ace
  15. Azasperones:
    Burspirone (Buspar)
  16. Tricyclic Antidepressants (2):
    • Amitriptyline (Elavil)
    • Clomipramine (Clomicalm)
  17. SSRI (2):
    • Paroxetine (Paxil)
    • Fluoxetine (Prozac)
  18. What Drugs can be used to Tx fear/phobias in dogs (3)?
    • Diazapam
    • Transene (Cloirazepate Dipotassium)
    • Alprazolam
  19. What Drugs are used to Tx general anxiety in dogs (3)?
    • Azapirones
    • Loarzapam (geriatrics)
    • SSRI
  20. What Drugs are used to Tx Seperation Anxiety in dogs (3)?
    • Diazapam
    • Clomipramine HCl (Clomicalm)
  21. What Drugs are used to Tx Anxiety in cats (4)?
    • Azapirones
    • Clomipramine HCl (Clomicalm)
    • Diazepam
    • SSRI's
  22. What drugs are used to Tx urine spraying in cats (4)?
    • Diazapam
    • Azapirones
    • SSRI
    • Clomipramine HCl (Clomicalm)
  23. What durgs are used to Tx Compulsive Behaviors in dogs (2)?
    • SSRI's
    • Clomipramine HCl (Clomicalm, Tricyclic)
  24. What drugs are used to Tx Sleep Disorders in dogs?
    MOI's
  25. What drugs are used to Tx Cognitive Dysfunction in dogs?
    MOI's
  26. What drugs are used to Tx depression in dogs and cats?
    Fluoxetine (SSRI)
  27. What drugs are used to Tx eating disorders in dogs and cats?
    Fluoxetine (SSRI)
  28. What drugs are used to Tx panic disorders in dogs and cats?
    Fluoxetine (SSRI)
  29. What drugs is used to Tx urine marking in Dogs and Cats?
    Amitriptyline
  30. What drugs are used to Tx hyperesthesia in cats?
    Clomipramine HCl (Clomicalm, Tricyclic)
  31. What drugs are used to Tx Acral Lick Dermititis in dogs
    Clomipramine HCl (Clomicalm, Tricyclic)
  32. What Drugs are used to Tx tail chasing/flank sucking in dogs?
    Clomipramine HCl (Clomicalm, Tricyclic)
  33. What drugs are used to Tx aggression?
    SSRI
  34. Tricyclic Antidepressants can be used with _(3)__ when single drug Tx's fail
    • Benxodiazapines
    • Buspirone
    • Trazadone
  35. SSRI's can be used with _(2)__ when single drug Tx's fail
    • Buspirone
    • Trazadone
  36. Benzodiazapines can be used with _(2)__ when single drug Tx's fail
    • MOI
    • TCA
  37. Baseline psychotrpoic drugs (3):
    • (Benzodiazapines)
    • Alprazolam
    • Lorazepam
    • Chlorazepam
  38. Atypical psychotropic Drugs (2):
    • Buspirone
    • Trazodone
  39. What drug can cause mortalities d/t cardiac abnormalities?
    Citalopram
  40. What is the 1/2 life for Fluoxetine HCl (Prozac)?
    4-16 days
  41. MOI's should not be given with... (2)
    • SSRI's
    • TCA's
  42. TCA's should not be given with... (3)
    • Cimetidine
    • Amitraz
    • Ketconazole
  43. What should no be given with TCAs b/c it inhibits cytochrome P-450?
    Cimetidine
  44. What drugs can cause serotonin syndrome?
    MOI's + Mitaban Dip, Preventic Collars, TCA or SSRI's
  45. What drugs affect learning processes (necessary for behavior modificiation)?
    • Benzodiazapines
    • Phenothiozines
  46. What drugs may facilitate learning?
    TCA's

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