CV drugs

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Anonymous
ID:
83078
Filename:
CV drugs
Updated:
2011-05-01 19:56:24
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CV drugs
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CV drugs
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  1. Types of CV Disorders (7)
    • Myocardial infarction
    • Congestive Heart Failure
    • HTN
    • Angina
    • Arrhythmias
    • Hyperlipidemia
    • Stroke
  2. Alpha 1 Adrenergic Blockers (3)
    • Doxazosin - Cardura
    • Terazosin - Hytrin
    • Tamsulosin
  3. Alpha 1 indications
    • BPH
    • HTN (not first line)
  4. Alpha 1 MOA
    • Blocks A1 receptors.
    • Causes dilation of peripheral arterioles and veins
    • Relaxes smooth muscle
  5. Alpha 1 blockers counseling points (4)
    • SE: orthostatic hypotension
    • Titrated dosing
    • May take 1-2 weeks to stabilize
    • Preg Cat C
  6. Alpha 2 adrenergic blockers (1)
    Clonidine - Catapres
  7. A2 indications
    • HTN (not first line)
    • ADHD (ER only)
    • Off label stuff
  8. A2 MOA
    • Stimulates A2 receptors in brainstem
    • Reduces symp output
    • Decreased peripheral resistance, heart rate and BP
  9. A2 counseling points
    • SE: orthostatic hypotension and CNS depression
    • Same as A1
  10. Nitrates (3)
    • Nitroglycerin
    • Isosorbide mononitrate - ISMO, Monoket
    • Isosorbide dinitrate - Isordil
  11. Nitrates indications
    • Angina pectoris
    • HTN
    • Hearth failure
  12. Nitrates MOA
    • Stimulate intracellular cGMP production
    • Vasodilation
  13. Nitrates counseling points
    • SE: Flushing
    • For acute angina, if pain persists after 5 mins call 911. May take up to 3 tablets.
    • Store SL tablets in tinted glass bottle
    • Preg Cat B/C
  14. Antiarrythmics (1)
    Amiodarone - Cordarone, Pacerone
  15. Antiarrythmics MOA
    • Block Na+ channel: slow intraventricular conduction
    • Block Badrenergic/Ca2+ channels: slow AV node conduction
    • Inhibits K+ channel: prolonged repol
  16. Antiarrythmics counseling points
    • SE: bradycardia, N/V/Dizziness, hypothyroidism, photosensitivity
    • Take with food
  17. Antiarrythmics Toxicity
    • Liver toxicity
    • Usually mild
    • Blue/gray skin
  18. Antiarrythmics 2 (1)
    Digoxin - Lanoxin
  19. Antiarrythmics 2 Indications
    • Hearth Failure (CHF)
    • Supraventricular arrhythmias
  20. Antiarrythmics 2 MOA
    • Inhibits Na+/K+/ATPase pumps
    • Normalizes HR and decreases conduction via AV node
  21. Antiarrythmics 2 Counseling Pointsq
    • SE: blurred vision, yellow/green halos
    • Take with lots of water
    • Tons of DDI
    • Narrow therapeutic index
  22. Antithrombolytics (3)
    • Warfarin - Coumadin
    • Clopidogrel - Plavix
    • Aspirin
  23. Antithrombolytics MOA
    • Warfarin - inhibit formation of vitamin K clotting factors
    • Clopidogrel - irreversibly binds to ADP receptors on platelets
    • Aspirin - covalently binds to COX enzymes
  24. Warfarin Counseling points
    • SE: bleeding, blood in stool
    • No EtOH
    • Avoid chances in diet (green leavy vegetables)
    • Do not DC abruptly
    • Narrow therapeutic index
    • Preg Cat X
  25. Clopidogrel Counseling points
    • SE: Bleeding, blood in stool
    • Avoid NSAIDS
    • Avoid Omeprazole, decreases effect
    • Preg Cat B
  26. Aspirin Counseling points
    • SE: N/V/D GI stuff
    • CI in children
    • Preg cat D in 3rd trimester

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