Antigen and Antibodies

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Author:
pdnguyen
ID:
83147
Filename:
Antigen and Antibodies
Updated:
2011-05-03 22:09:28
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Antigen Antibodies
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Antigen and Antibodies
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  1. L-aspariginase
    lymphomas
  2. Imatinib mesylate
    Bcr-Abl
  3. Dasatinib
    Bcr-Abl, SRC, PDGFR-Beta
  4. Lapatinib
    EGFR, HER-2
  5. Gefitinib
    EGFR-TK
  6. Erlotinib
    EGFR-TK
  7. Atretinoin
    RXR
  8. Bexarotine
    RXR
  9. Arsenic Trioxide
    APL
  10. Thalidomide
    Bcl-2
  11. Lenalidomide
    Bcl-2
  12. Bortezomib
    Inhibit chymotrypsin-like activity of 26S proteosome
  13. Porfimer
    ROS
  14. Temsirolimus
    FKBP-12
  15. Combretastatin
    Binds to tubulin
  16. Zoledronic
    Inhibit bone matrix-degrading proteinases
  17. Goserelin acetate
    D-Ser
  18. Leuprolide acetate
    D-leu
  19. Octreotide
    Inhibit GnRH receptor
  20. Estramustine
    form aziridinium ion
  21. Tamoxifine
  22. non-steroidal
  23. Fulvestrant
    Steroidal
  24. Flutamide
    non-steroidal
  25. Letrozole
    • non-steroidal
    • triazole ring + heme iron of aromatase enzyme
  26. Exematase
    steroidal
  27. Denileukin diftitox
    Recombinant IL-2 + diphtheria toxin
  28. Rituximab
    CD20 Ag of B-lymphocytes
  29. Trastuzumab
    ADCC overexpressing HER2
  30. Bevacizumab
    Inhibit VEGF (IgG1)
  31. Panitumumab
    Inhibit EGFR (IgG2)
  32. Cetuximab
    Inhibit EGFR (IgG1)
  33. Edrocolomab
    Inhibit EpCAM
  34. Gemtuzumab oxogamicin
    • Calicheamicin
    • CD33
  35. Ibritumomab
    Inhibit CD20 Antigen on B cells
  36. Toxitumomab
    CD20 of B cells
  37. Anti-PSMA mAb
    • Deimmunized murine IgG2
    • Against PSMA

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