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Name one hypokinetic disorder
Name some hyperkinetic disorders
What is the age of onset for Parkinson's disease
Which movement condition is the most multi-factorial and idiopathic?
What are some other causes for Parkinson's disease?
- Maganese Intoxication
- Multiple cerebral infarcts
- Swine Flue
What are some clincal features of Parkinson's disease?
- cogwheel rigidity (stiff movements)
- resting tremor (pill rolling, looks like picking at clothes)
- loss of writing reflexes
What is BradyKinesia?
Slowed ability to start and continue movements.
By age 70, how much has the dopamine in the substantia nigra decreased?
Dopamine excess = ?
How can you treat dopamine excess?
- Globus Pallidus Ablation
- Deep Brain Stimulation: Shuts off subthalamic nucleus of luys
Hemiballismus is always due to ________
What is the clinical feature of hemiballismus?
severe contralateral flinging movements
Which is more common, Parkison's or Hemiballismus?
What is the age of onset for hemiballismus?
What are some behavioral changes for someone with Hemiballismus?
depression, mood swings
What are some abnormal movements of Hemiballismus?
- Chorea-involuntary movements
- Athetosis-slow writhing movements, confined to limbs
What is missing in huntington's disease
Caudate--or else it can't receive dopamine, so it leads to too much dopamine
Hemiballismus is due to
stroke in the subthalamic nucleus and results in excess movements on the contralateral side
T/F: Huntington's disease is caused by autosomal dominant mutation
What types of medicine can treat Parkinson's disease?
L-Dopa and Dopacrboxylase
Damage in the __________ causes hemiballismus
Subthalamic nucleus of luys