PHAR CH 19

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Author:
leti563
ID:
83774
Filename:
PHAR CH 19
Updated:
2011-05-04 16:52:52
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PHAR
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CH 19
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  1. ANALGESICS
    Pain relievers
  2. OPIATE ANALGESICS
    • For severe pain (NARCOTIC)
    • 1. Natural opium alkaloids
    • 2. Synthetic Opioids

    SE's: May cause tolerance or dependance
  3. OPIATE ANTAGONISTS
    Narcan
  4. OPIATE ANALGESICS
    NATURAL
    Morphine & Codeine
  5. OPIATE ANALGESICS
    SYNTHETIC
    • Hydrocodone
    • mederidine
    • oxycodone
  6. NON OPIATE ANALGESICS
    (4 types)
    • Salicylates
    • Non steroidal Anti- Inflamatory Drugs (NSAID)
    • acetaminophen
    • tramadol
  7. SALICYLATES
    acetalsalicylic acid (Aspirin)

    SE's : GI Bleeding, bruising, tinnitus
  8. NON SEROIDAL ANTI-INFLAMMATORY DRUGS (NSAID)

    2 types
    Relieves oain by reducing inflamation.

    2 types

    • Nonsteroidal
    • corticosteroids
  9. ACETAMINOPHEN
    widely used w fewere SE's than NSAID's

    No anti inflammatory effect.
  10. tramadol
    Centrally acting, mimics opiates but its not a narcotic.

    Not a controlled drug.
  11. ANTIMIGRAINE DRUGS
    Serotonin Receptor Agonists
  12. Sumatriptan (Imitrex)
    Vasoconstricion

    Caution; In patients w heart disease.
  13. SEDATIVES AND HYPNOTICS
    Used to induce sleep
  14. OTC BRANDS
    Contain antihistamines
  15. dyphenhydramine
    • Benadryl
    • Nytol
  16. BARBITURATES
    Controlled drugs

    Accidental overdoses common
  17. phenobarbitol (Luminol)
    Respiratory depression.
  18. Benzodiazepines
    Many uses

    • Short term anesthesia
    • Delerium Tremens (alcohol w/drawal)
  19. midazolam (Versed)
    Short term anesthesia.

    SE's: Respiratory Deppression
  20. lorazepam (Ativan)
    Alcohol withdrawal

    SE's: Respiratory Deppression
  21. HOW DO NSAID'S WORK
    By blocking formation of PROSTAGLANDIN, a chemical that produces inflamation and pain of many conditions. such as

    • Arthritis
    • Sprains
    • Menstrual Cramps

    Prostaglandins are made using cyclo oxygenase (COX) enzymes.
  22. Traditional NSAID's
    • ibuprofen (Motrin, Advil)
    • indomethacin (indocin)
    • ketorolac (Toradol)
  23. COX-2 INHIBITORS (Celebrex)
    Bloc only the COX-2 enzymes and lower prostaglandin.

    Leaves COX-1 Unblocked, and protects gastric mucosa

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