Virology T7 and Lambda
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T7 and lambda's virions are __?__.
- Naked icosahedral
- T7 has a short tail
- Lambda has a long flexible tail
T7 life cycle includes __?__.
- 1. Adsorption (attachment through tail fiber)
- 2. Injection of DNA
- 3. Trx/Tln early genes
- 4. Replication
- 5. Trx/Tnl late genes
- 6. Assembly in cytoplas
- 7. Release by lysis
Genome is organized as __?__.
Class 1 (early), 2 (rep.), and 3 (structure/assembly) which are clustered by function and timing
DNA entry is characterized by __?__. (x4)
- bacterial RNA pol recognition
- Spooling (coupled to trx)
- At TE sequence bacterial pol releases mRNA and viral pol takes over
Lambda is a good example of a viruse that has __?__ or __?__ life cylces.
Induction is: __?__. and is controlled by __?__.
The switch from lysogeny to lytic modes and is controlled by CL (represses Pr and Pl) and CRO (represses Prm to cont turn down Pr and Pl)
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