Card Set Information
Papilla- means __?__.
referring to warts (pappiloma)
Papilloma's virion is __?__
Papilloma's genome is __?__
circular dsDNA packaged as "minichromosomes"
Papilloma's genes and proteins are expressed:
From two promoters and two poly A signals (early and late) from 1 DNA strand
Early= E1-7 - stimulate cell proliferation and enable DNA rep
Late = L1-2 form capsid
Papilloma examples include:
Papilloma's distinct characteristics include __?__. (3)
Replication pattern follows differentiation of epithelial cells in skin or mucosa
and 7 regulate
and pRb (
E2 downregulates E6 and 7 - regulatory sys
Papilloma and polyoma were in the same group "papova" (which means __?__) until it was discovered __?__ which seperated them into thier own families.
Polyoma needs both DNA strands to replicate