Neuro 56 learning.txt

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  1. test used for immediate memory?
    Digit Span: List of numbers and read forwards/backwards
  2. Short term memory test?
    breakfast, story of morning, or some other recent event
  3. Long -term memory test?
    Something important in their life (War, marriage, deaths, etc...)
  4. What would an alzheimer's/stroke patient remember?
    Many memories before the onset of the event
  5. Anterograde amnesia?
    can't remember anything new since the surgery or traumatic event
  6. retrograde amnesia?
    Can't remember past
  7. 4 steps of memory loop
    • 1) sensory processed in cortical areas
    • 2) info transferred to association areas of temporal lobe
    • 3) info consolidated in hypo/amyg
    • 4) when needed, info returned to association cortex (prefrontal, temporal, diffuse cortical areas)
  8. Right hippocampus functin?
    Places, maps
  9. Left hippocampal function?
    words, lists, languages
  10. Long-term potentiation (LTP) pathway?
    • Sensory info into hippocampus
    • pre-synaptic glutamate release
    • Post-synaptic glutamate receptors (NMDA) open
    • Ca influx into cells
    • feedback to produce more glutamate and receptors
    • surface area increases
    • **Strengthen synapse after info bombardment
  11. Amygdala function?
    Receive sensory info and build memories to negative events
  12. How amygdala functions?
    • LTP-like
    • SNS
  13. 5 signs of Kluver-Bucy syndrome
    • Hypersexuality
    • Hyperattentive
    • Hyperorality
    • visual agnosia
    • Placidity
  14. Kluver-Bucy syndrome causes?
    Temporal and Amygdala nuclei damage
  15. three Chemical memory modulators?
    • Choline: attention
    • NE/Epi: vigilance/attention
    • GABA: inhibition
  16. Cholinergic agonists?
    Acetylcholinesterase inhibitor
  17. Adrenergic agonists?
    • Epinephrine
    • Caffeine
    • Amphetamine
  18. Choline antagonist?
  19. Physostigmine, Tacrine, Aricept, Exelon
    Cholinergic agonists (AchE antagonists)
  20. Versed?
    GABA agonist
  21. Propranolol?
    • B-adrenergic antagonists
    • Can block LTP
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Neuro 56 learning.txt
Neuro 56 learning
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