Pharmacology Chapter 12

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tswhite
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84103
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Pharmacology Chapter 12
Updated:
2011-05-05 22:48:29
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Leukotrienes
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Pharmacology Study Guide Chapter 12
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  1. The general indication for clinical use of nonsteroidal antiasthma agents is:
    A. short-term control of bronchospasm
    B. long-term control of bronchospasm
    C. control of severe asthma attack
    D. prophylactic management of mild persisten asthma
    D. prophylactic management of mild persisten asthma
    (this multiple choice question has been scrambled)
  2. Nonsteroidal antiasthma drugs are:
    A. relievers
    B. b2 antagonists
    C. antiinfectives
    D. controllers
    D. controllers
    (this multiple choice question has been scrambled)
  3. The brand name for cromolyn sodium is:
    A. Singulair
    B. Intal
    C. Tilade
    D. Accolate
    B. Intal
    (this multiple choice question has been scrambled)
  4. Cromolyn sodium is available in all of the following forms except:
    A. neb
    B. tablet
    C. MDI
    D. nasal spray
    B. tablet
    (this multiple choice question has been scrambled)
  5. Which of the following are antileukotrienes?
    I. Zafirlukast
    II. Zileuton
    III. Cromolyn Sodium
    IV. Montelukast
    V. Nedocromil Sodium
    A. I, II, and III only
    B. I, II, and IV only
    C. III and V only
    D. II, IV, and V only
    B. I, II, and IV only
    (this multiple choice question has been scrambled)
  6. Cromolyn sodium is effective in preventing bronchospasm by:
    A. blocking cholinergic receptor sites
    B. stimulating b2-adrenergic sites
    C. inhibiting mast cell degranulation
    D. enhancing mast cell degranulation
    C. inhibiting mast cell degranulation
    (this multiple choice question has been scrambled)
  7. The most commonly reported side effect of cromolyn sodium is:
    A. nasal congestion
    B. diarrhea
    C. pneumonia
    D. headache
    A. nasal congestion
    (this multiple choice question has been scrambled)
  8. The usual dose of nebulized cromolyn sodium is:
    A. 80 mg 3xday
    B. 30 mg 3xday
    C. 10 mg 4xday
    D. 20 mb 4xday
    D. 20 mb 4xday
    (this multiple choice question has been scrambled)
  9. Nedocromil Sodium is administered by:
    A. tablet
    B. dpi
    C. neb
    D. MDI
    D. MDI
    (this multiple choice question has been scrambled)
  10. Tilade is effective as an intiinflammatory by inhibiting activation and activity of which of the following?
    I. sensory neurons
    II. mast cells
    III. airway epithelial cells
    IV. eosinophils
    A. II only
    B. I, II, and IV only
    C. I and II only
    D. I, II, III, and IV
    D. I, II, III, and IV
    (this multiple choice question has been scrambled)
  11. It has been suggested that intal and tilade are effective as antiinflammatory agents by blocking transport of what ion into inflammatory celss?
    A. chloride
    B. potassium
    C. sodium
    D. bicarbonate
    A. chloride
    (this multiple choice question has been scrambled)
  12. Leukotrienes exhibit which of the following effects?
    I. incr mucus secretion
    II. inhibition of normal ciliary action
    III. incr airway edem
    IV. bronchoconstriction
    V. recruitment of other inflammatory cells into airways
    A. I, II, and IV only
    B. IV only
    C. III, IV, V only
    D. I, II, III, IV, and V
    D. I, II, III, IV, and V
    (this multiple choice question has been scrambled)
  13. Zileuton interacts with which of the following respiratory care drugs?
    I. theophylline
    II. albuterol
    III. warfarin
    IV. ipratropium bromide
    V. beclamethasone
    A. I and III only
    B. III and V only
    C. II and IV only
    D. I and V only
    A. I and III only
    (this multiple choice question has been scrambled)
  14. Zafirlukast is a :
    A. corticosteroid
    B. B adrenergic
    C. leukotriene receptor stimulator
    D. leukotriene receptor antagonist
    D. leukotriene receptor antagonist
    (this multiple choice question has been scrambled)
  15. The only antileukotriene agent currently approved for use in ped patients:
    A. intal
    B. singulair
    C. accolate
    D. tilade
    B. singulair
    (this multiple choice question has been scrambled)
  16. What is clinical indication for use of leukotriene modifiers, such as montelukast, in asthma?
    A. mast cell stabilizer
    B. as a long-acting bronchodilator in step 3 asthma
    C. alternative to or in combo with inhaled steroids
    D. rescure bronchodilator in step 1 asthma
    C. alternative to or in combo with inhaled steroids
    (this multiple choice question has been scrambled)
  17. After a patient begins cromolyn sodium, how long may it take to show improvement in symptoms?
    A. 2-4 weeks
    B. 1-3 months
    C. 24 hours
    D. 4-6 days
    A. 2-4 weeks
    (this multiple choice question has been scrambled)
  18. Which of the following is considered a mast cell stabilizer?
    A. cromolyn sodium
    B. zileuton
    C. zafirlukast
    D. montelukast
    A. cromolyn sodium
    (this multiple choice question has been scrambled)
  19. Which of the following nonsteroidal antiasthma agents is formulated as an MDI?
    A. nedocromil
    B. zafirlukast
    C. zileuton
    D. montelukast
    A. nedocromil
    (this multiple choice question has been scrambled)
  20. Which of the following is a monocolonal antibody used to reat asthma?
    A. nedocromil
    B. omalizumab
    C. montelukast
    D. zileuton
    B. omalizumab
    (this multiple choice question has been scrambled)
  21. Advantages to the use of antileukotrienes include all of the following except:
    A. effective in more than 90% of patients
    B. additive effect w/ inhaled steroids
    C. a formulation availabe for ped use
    D. oral admin
    A. effective in more than 90% of patients
    (this multiple choice question has been scrambled)
  22. Which drug is a lipid-soluble, intracellular receptor agonist that prevents inflammatory response?
    A. singulair
    B. flovent
    C. xolair
    D. zyflo
    B. flovent
    (this multiple choice question has been scrambled)

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