Card Set Information
what is eczema?
an inflammatory dermatosis
what are the 3 main features that characterise eczema?
what are the 9 types of eczema?
: most common, genetic, asthma & hayfever
: blistering hands and feet (stress)
lichen simplex chronicus
what is seborrheic eczema? who and where?
babies - cradle
t zones, nasolabial folds, groin
what is atopy?
predisposition to develop asthma, allergic rhinitis and atopic eczema
what are the blood signs of atopy?
increased IgE response
how is atopy diagnosed?
don't need to do blood tests
who is atopic eczema common in?
what % of atopic eczema have FHpositive?
where does eczema affect on children?
what are the main exacerbating factors for atopic dermatitis?
: detergents, soap (as people with eczema don't have same barrier function)
: bacterial (staph-impetigo), eczema herpeticum, molluscum
(house dust mite and food allergies)
what is the prognosis of atopic dermatitis?
50% clear by 3 years
66% clear by 6 years
90% clear by 20 years
how would you describe eczema herpeticum?
what can happen to skin if keep itching?
: generalised thickening of skin, becomes rough and tough, can see skin markings
what are the 5 main aspects to treatment of atopic dermatitis?
1. avoid provoking factors eg soap
2. reduce dryness
: bath oils, soap substitutes, emollients
3. topical corticosteroids
: for active inflammation
4. anti-histamines (make sleepy) /bandaging (stop scratching)
5. Rx secondary infections
which is the strongest steroid cream for eczema?
what are the 3 SE from steroid creams?
1. potential systemic absorption
2. skin atrophy (prominence of bv, skin fragile)
3. acne/perioral dermatitis
if first line Rx don't work for atopic dermatitis, then what are next line Rx?
: calcineurin inhibitor, immune modulator, use if too many SE of steroids or need too high dose of steroids
: PUVA or UVB (immune suppressant)
: systemic steroids, azathioprine, cyclosporin A
what are the main SE of ciclosporin
immune suppress - so cancer risk
what is contact dermatitis?
inflammation due to interaction of external agent and the skin
usually well demarcated/confined to area of contact
what are the 2 types of contact dermatitis?
non-immunological = IRRITANT (80%)
immunological = ALLERGIC (20%)
who gets irritant contact dermatitis?
new nurse or new mum
the irritant leads to inflammation when applied to the skin or most normal people
who gets allergic contact dermatitis?
people with type 4 or delayed cell mediated hypersensitivity
give an eg of an acute and a chronic allergic contact dermatitis?
: ie nickel, fragrances, hair dye
what reasons would make you suspect contact dermatitis?
acute/chronic eczema not responding/aggravated by Rx
work related - nurse(latex gloves), hairdresser hair dye
how do you make the diagnosis of allergic contact dermatitis?
history of allergen exposure
what is the Rx for allergic contact dermatitis?
what is pompholyx eczema?
where does pomphloyx eczema occur?
get tiny blisters on fingers > soles
what is the Rx of pompholyx eczema?
potent topical steroids
describe the vesicles of pomphloyx eczema?
may be painful
what are the lesions of nummular/discoid eczema like?
coin shaped lesions
may be vesicular and colonised with staph aureus
where does nummular/discoid eczema occur?
what is Rx of num/discoid eczema?
often difficult to Rx
potent topical steroids
who does seborrheic eczema affect?
infants 2-10 weeks
where in infants does seb eczema come?
intertriginous areas - where 2 surfaces come together eg groin, neck fold, armpits
where in adults does seb eczema affect?
describe the rash of seborrheic eczema?
what is the Rx of seborrheic eczema?
topical steroids + scalp application
what is erythroderma?
when >90% of the body is affected by erythema and scaling
what are the 4 causes of erythroderma to consider?
what is the Rx of erythroderma?
treat secondary infection
treat underlying causes if known
what is differential diganosis of eczema?
: seborrheic dermatitis, irritant dermatitis
: candida, strep/staph, tinea cruris