Micro final

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Author:
trsmith
ID:
84930
Filename:
Micro final
Updated:
2011-05-09 23:29:44
Tags:
micro biology
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Description:
exotoxin and endotoxins
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  1. clostridium botulinum
    • #1 lethal cause of food poisoning
    • signs are
    • 1) foul odor
    • 2) foul taste
    • 3) turns black +H2S (cysteine desulfurase)
    • 4) inconsistency of the food

    #1 canned food to get botulism is green beans

    exotoxin
  2. Virulence
    an organisms ability to cause a disease
  3. Invasiveness
    the ability of an organism to get into a host

    • more invasive=less toxic-tick
    • less invasive= more toxic
  4. toxicity
    poison
  5. short generation time
    virulence factor

    + because they multiply quickly
  6. presence of a spore
    • virulence factor
    • highly resistant to extreme temps
    • endospore-within a rod
    • terminal spore- at the end of a rod
    • +
  7. presence of a capsule
    • virulence factor
    • protein = -body stimulation

    #1 antigen on planet

    polysaccharide=+ #2 antigen
  8. Motility
    • +VF
    • virulence factor
    • can get away from a WBC
    • 4 flag arranrgements
  9. coagulase
    VF - enzyme

    clots serum
  10. Hyaluronidase
    • digests hyaluronic acid - which in cement mordant or glue that holds cells together
    • enzyme
  11. Streptokinase/staphylokinase
    • produced from strep. and staph.
    • digests fibron clots

    • WBC-7500/mm3
    • platelet 250000/mm3
    • RBC 5.1x10 6/mm3

    enzyme-VF
  12. Blood clotting mechanism
    • prothroman calcium vitK > thrombin
    • liverprotein thromboplasim
    • found in cells

    Fibrinagen thrombin liver protein > fibrin -clot of blood / sticky
  13. Hemolysin
    lyses blood cells (red+white) 1-10

    +VF
  14. lecithinase
    breaks down muscle membrane (epimysium) + VF
  15. exotoxin
    • Mostly gram - ecoli
    • secreted by the cell as a waste product
    • specific effects -nerotoxins-nerve cells
    • infects neurons
    • effects muscles
    • heat labile-broken sown 56-60*c for 1hr
    • symptoms are quickly produced and results are more severe
  16. endotoxin
    • mostly gram +
    • released opon lysis of the cell
    • nonspecific effects -fever diarrhea
    • heat stable 56-60*c for 1hr
    • results in less toxic situation

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