Neutropenic Fever

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Author:
Anonymous
ID:
8589
Filename:
Neutropenic Fever
Updated:
2010-03-01 02:16:42
Tags:
Neutropenic Fever
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Description:
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  1. definition of a fever
    • single oral of 101
    • greater than 100.4 for more than 1 hour
  2. How to calculate ANC
    ANC = WBC x % Neutrophils

    %Neutrophils = %bands + % segs
  3. At onset of signs and symptoms of infection, what should be done with afebrile patients?
    started on empiric therapy
  4. High risk of infection
    • Prolonged neutropenia (>7 days)
    • Uncontrolled malignancy
    • Hypotension
    • Complex infection
    • Significant comorbidities
  5. If patient remain febril through the first 5-7 days, what should be initiated
    antifungal drug with or without antibiotic change
  6. 48 hours after afebrile and ANC greater than 500
    stop antibiotics
  7. If ANC is less than 500 by 7, initial low risk, clinically well, antibiotics can be stopped when?
    the patient is afebrial for 5-7 days
  8. If ANC < 500 by day 7, initial high risk (<100, mucositis, unstable signs)
    continue anitibiotics
  9. if persistent fever and ANC > 500
    stop 4-5 days after ANC > 500
  10. if persistent fever and ANC < 500
    continue for 2 weeks

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