photosensitivity = common for sulfa drugs = long sleeves =) sunburn
discoloration of urine/skin are most common
less common = reduced WBC/RBC counts
Watch out !!
not to be used with existing CNS disorders
drug interaction studies have not been conducted
may reduce the response of the immune system (caution if pt has condition that suppresses the immune system OR when an immune response is desired such as a vaccination and DO NOT USE if there is an active infection)
Adverse Events !!
most common = redness, itching, pain, or swelling at the site of injection
reverses response of immune system
"biologic response modifier"
depressing immune system
knock out ability of immune system to respond to inflammation
Watch out !!
do not use if pt taking "gold salts"
cytotoxic drugs (rheumatrex)
because of similar bone marrow and kidney risks
weakens collagen therefore reduce the dose when surgery is considered/resume after the wound has healed
rash (itching may be pretreated with antihistamines to decrease)
if rash is accompanied by fever/joint pain = discontinue
loss of the tense of taste
bone marrow suppression serious kidney disease
need compliant pt
all pts who take penicillamine require regular blood and urine testing for monitoring
may induce immune-mediated diseases
you're born with it
acquired or adaptive
you develop it
Purpose of vaccines
trick the body into producing antibodies against a harmless imposter
then, if the real microbe turns up, the body's defenses are primed to foil infection and disease
Why are vaccines administered ??
not to cure or manage disease but to prevent it
Why do we use it ?
to create rapid but temporary immunity because pt was exposed to something
made up of pooled protein from 100's of people so like giving wrong blood
prior allergic reaction
recent or proposed live virus vaccination
recent or proposed allergy testing (may create false positive)
pregnancy & lactation (weigh risk vs. benefit)
local pain/tenderness at the injection site
anaphylactic reactions, although rare, have been reported-keep epinephrine on hand and observe pt closely after injection
gives passive immunity - so chicken pox vaccine will not work
stay with pt for 20-30 minutes after given
any vaccines processed or planned - re-vaccinate or postpone vaccine