CHAPTER 23 ENDOCRYNE SYSTEM DRUGS

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leti563
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86508
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CHAPTER 23 ENDOCRYNE SYSTEM DRUGS
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2011-05-18 00:17:27
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CHAPTER ENDOCRYNE SYSTEM DRUGS
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ENDOCRYNE SYSTEM DRUGS
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  1. HORMONES
    REGULATING HORMONES
    Secreted to other endocrine glands.
  2. HORMONES
    ACTIVE HORMONES 4
    • Thyroxine- thyroid gland
    • Cortisol- adrenal glands
    • Estrogen- from ovaries
    • Testosterone- Testes
  3. ADRENAL CORTICODTEROIDS
    ADREAL ANATOMY
    Stimulated adrenal cortex to secrete the main corticosteroid called cotisol.
  4. ADRENAL CORTICOSTEROIDS
    ADRENAL INSUFFICIENCY
    Addison's disease

    Causes: Autoimmune, infection.
  5. ADRENAL CORTICOSTEROIDS
    ADRENAL OVERPRODUCTION
    Cushing's syndrome

    Causes: Pituitary tumor, Cortisol treatment.
  6. CORTICOSTEROID AGENTS
    USES:
    • Inflammatory conditions:
    • Allergic reactions
    • Rheumatoid arthritis- oral injectable
    • Skin conditions- Topical
    • Asthma- Inhaled
    • Organ transplantation to prevent rejection.
  7. CORTICOSTEROID AGENTS
    SIDE EFFECTS:
    • Delayed wound healing
    • Increased risk of infection
    • Osteoperosis (Bone loss)
    • Hyperglycemia and diabetes.
    • Mood swings, depression
  8. CORTICOSTEROID AGENTS
    PRECAUTIONS:
    • Avoid prolonged use
    • Discontinue gradually
  9. THYROID AGENTS
    HYPOTHYROIDISM
    Reduced activity of the thyroid gland.
  10. THYROID SUPPLEMENTS
    Levothyroxine (Synthroid)
    Synthetic thyroid compounds are more accurately dosed..

    SE's: Tachychardia, palpitations, hypertension.
  11. THYROID SUPPRESSIVE AGENTS
    Hyperthyroidism - Graves disease

    Causes: Autoimmune 60's- 70's
  12. ANTIDIABETIC AGENTS
    INSULLIN
    Hormone produced in the pancreas
  13. DIABETES MELLITUS
    Syndrome of hyperglycemia (elevated blood sugar)
  14. DIABETES
    LONGS TERM EFFECTS
    • Cardiovascular disease
    • Kidney failure
    • Blindness
    • Nerve Damage
  15. DIABETES
    tREATMENT
    • Diet
    • Medication
    • -Insulin for type 1
    • -Oral antidiabetic agents for type 2
  16. INSULIN PRODUCTION/ RESISTANCE
    Destroyed by stomach acids. Must be injecte sub Q.

    Classified in 2 ways: Onset Duration of action.
  17. ORAL ANTIDIABETIC AGENTS
    along w diet cchanges. oral changes may control blood sugar w out the need for insulin.

    Used mainly in type 2 diabetes.

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