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HORMONES
REGULATING HORMONES
Secreted to other endocrine glands.
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HORMONES
ACTIVE HORMONES 4
- Thyroxine- thyroid gland
- Cortisol- adrenal glands
- Estrogen- from ovaries
- Testosterone- Testes
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ADRENAL CORTICODTEROIDS
ADREAL ANATOMY
Stimulated adrenal cortex to secrete the main corticosteroid called cotisol.
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ADRENAL CORTICOSTEROIDS
ADRENAL INSUFFICIENCY
Addison's disease
Causes: Autoimmune, infection.
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ADRENAL CORTICOSTEROIDS
ADRENAL OVERPRODUCTION
Cushing's syndrome
Causes: Pituitary tumor, Cortisol treatment.
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CORTICOSTEROID AGENTS
USES:
- Inflammatory conditions:
- Allergic reactions
- Rheumatoid arthritis- oral injectable
- Skin conditions- Topical
- Asthma- Inhaled
- Organ transplantation to prevent rejection.
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CORTICOSTEROID AGENTS
SIDE EFFECTS:
- Delayed wound healing
- Increased risk of infection
- Osteoperosis (Bone loss)
- Hyperglycemia and diabetes.
- Mood swings, depression
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CORTICOSTEROID AGENTS
PRECAUTIONS:
- Avoid prolonged use
- Discontinue gradually
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THYROID AGENTS
HYPOTHYROIDISM
Reduced activity of the thyroid gland.
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THYROID SUPPLEMENTS
Levothyroxine (Synthroid)
Synthetic thyroid compounds are more accurately dosed..
SE's: Tachychardia, palpitations, hypertension.
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THYROID SUPPRESSIVE AGENTS
Hyperthyroidism - Graves disease
Causes: Autoimmune 60's- 70's
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ANTIDIABETIC AGENTS
INSULLIN
Hormone produced in the pancreas
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DIABETES MELLITUS
Syndrome of hyperglycemia (elevated blood sugar)
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DIABETES
LONGS TERM EFFECTS
- Cardiovascular disease
- Kidney failure
- Blindness
- Nerve Damage
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DIABETES
tREATMENT
- Diet
- Medication
- -Insulin for type 1
- -Oral antidiabetic agents for type 2
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INSULIN PRODUCTION/ RESISTANCE
Destroyed by stomach acids. Must be injecte sub Q.
Classified in 2 ways: Onset Duration of action.
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ORAL ANTIDIABETIC AGENTS
along w diet cchanges. oral changes may control blood sugar w out the need for insulin.
Used mainly in type 2 diabetes.
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