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What are the indications for ACEI's?
Prevention of progressive renal failure
Precautions of ACES's
Angioedema - increases risk!
Hypovolaemia, dehydration - increases risk of hypotension
Treatment of drugs that Increase K+ concentration or renal impairment
Adverse effects of ACEI"S
hypotension, cough, hyperkalemia, headache
angioedema, rash, elevated aminotransferases
Counselling for ACEI's?
May feel dizzy at first, get up slowly
Do not take K+ supplements
Dose of Elanapril?
whats it avaliable in combination with?
- HTN - 5mg daily, increase up to 10-40mg.
- HF- 2.5mg daily - increase upto 10-20mg
Dose of fosinopril?
10mg once daily, increasing upto 40mg
Dose of lisinopril?
HTN- 5-10mg once daily
HF - 2.5mg daily
MI - 5mg within 24 hours
Dose of perindopril?
Dose of ramipril?
- HTN - 2.5mg daily increase to 5mg
- HF - 2.5mg twice daily
Dose of trandolapril?
1mg daily, max 4mg daily