CCBs

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Author:
jmartin9
ID:
86875
Filename:
CCBs
Updated:
2011-05-20 07:04:26
Tags:
CCBs
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Description:
CCBs
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  1. Indications of CCBs?
    • Hypertension
    • Angina
    • SVT and AF} - verapamil
  2. Precautions of CCBs?
    • myasthenia-like neuromuscular disease
    • increased risk of muscle weakness and respiratory depression
  3. Does dyhydropyridine-induced peripheral odema require diuretic treatment? why or why not?
    no, due to risk of volume depletion
  4. Dose and adverse effects of amlodipine?
    dose: 2.5-5mg daily

    headache, flushing, peripheral oedema and palpitations

    pulmonary oedema, hypotension, tachycardia, chest pain, dyspepsia, constipation, paraesthesia, muscle cramps, rash
  5. Dose of diltiazem? in HTN and HF?

    adverse effects?
    HTN - 180-240mg daily

    peripheral oedema, rash, headache, dizziness, flushing, nausea, abdominal pain, bradycardia
  6. Dose of felodipine?

    Adverse effects?
    5mg daily

    headache, flushing, peripheral oedema and palpitationspulmonary oedema, hypotension, tachycardia, chest pain, dyspepsia, constipation, paraesthesia, muscle cramps, rash
  7. Lercanidipine
    C/I's??
    Dose?
    A/E?
    cyclosporin

    10mg daily

    headache, flushing, peripheral oedema and palpitationspulmonary oedema, hypotension, tachycardia, chest pain, dyspepsia, constipation, paraesthesia, muscle cramps, rash
  8. Nifedipine
    dose?
    Uses?
    A/E?
    10-20mg twice daily, increase to 20-40mg twice daily

    CR tablets preferred for angina use

    can be used for pre-term labour

    headache, flushing, peripheral oedema and palpitationspulmonary oedema, hypotension, tachycardia, chest pain, dyspepsia, constipation, paraesthesia, muscle cramps, rash
  9. Verapamil
    dose?
    Issue with dabigatran?
    Counselling point?
    Adverse effects?
    • 80mg two or three times daily upto 160 2-3x daily
    • 180-240mg CR

    Can increase concentration of dabigatran therefore increase bleeding risk

    Counselling: may increase effects of alcohol, swallow CR tabs whole

    • peripheral oedema, rash, headache, dizziness, flushing, nausea, abdominal pain, constipation
    • gynaecomastia, hepatitis

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