Diphenhydramine

Card Set Information

Author:
quaydud3
ID:
87759
Filename:
Diphenhydramine
Updated:
2011-05-25 20:50:29
Tags:
Pharmacology
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Description:
Pharmacology
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  1. Description
    Antihistimine administered after epinephrine in the treatment of anaphylaxis; blocks histimine receptors. When stimulated H1 receptors cause bronchoconstriction and contraction of the gut and H2 receptors produce perpheral vasodilation and secretion of gastric acids.
  2. Mechanism of Action
    Diphenhydramine is a potent antihistamine that blocks both histimine receptors (H1 and H2)
  3. Indications
    Anaphylaxis, allergic reactions, urtcaria, extrapyramidal (EPS) reaction-A response to a drug marked by uncontrolled movements, changes in muscle tone, and abnormal posture.
  4. contrainindications
    Benadryl should not be used in the management of lower-respiratory diseases such as asthma.
  5. Precautions
    Hypotension, headache, palpatations, and tachycardia have been known to occur following administration of Benadryl. Sedation, drowsiness, and disturbed coordination are common.
  6. Dosage and Administration
    • Standard dose of Benadryl is 25.0-50.0mg
    • For antihistimine effects: 12.5-25mg IM followed by 12.5-25mg IV
    • Pediatric dose-1mg/kg

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