Norepinephrine (Levophed)

Card Set Information

Author:
mcarter
ID:
88033
Filename:
Norepinephrine (Levophed)
Updated:
2011-05-27 13:35:52
Tags:
Norepinephrine Levophed
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Description:
Paramedic Drugs
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  1. Class
    Sympathetic agonist
  2. Description
    Naturally occurring catecholamine. It acts on both Alpha and Beta adrenergic receptors. However, its action on alpha receptors is more profound.
  3. Mechanism of Action
    Norepinephrine is a naturally occurring catecholamine and causes vasoconstriction, cardiac stimulation, and increases blood pressure, myocardial oxygen demand, and coronary blood flow.
  4. Onset of Action
    • Onset: Immediate
    • Peak: <1min
    • Duration: 1-2min
    • Half-Life: 3min
  5. Indications
    is used in hypotension refractory to other sympathomimetics and not used related to hypovolemia and in neurogenic shock.
  6. Contraindications
    Pt with hypotension from hypovolemia
  7. Precautions
    Can be deactivated by alkaline solutions, constant monitoring of BP is essential, Extravasation can cause tissue necrosis.
  8. Side Effects
    Anxiety, headache, hypertension, palpitations.
  9. Adult Dose
    0.5-1ug/min (AHA recommendation) but you may go to 30ug.min if absulutely necessary. 8mg should be placed in 500ml of D5W giving a concentration of 16ug/ml.
  10. Pedi-Dose
    .01-.5ug/kg/min (Rarely Used)
  11. Max dose
    30ug/min
  12. Routes of Administration
    IV drip only
  13. How Supplied
    Vials

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