Promethazine (Phenegran)

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  1. Description
    An antihistimine frequently used to treat nausea and vomiting; often administered with analgesics (narcotics) to enhance the effect and lessen chances of nausea
  2. Mechanism of Action
    Has potent antihistamine effects, An effective and commonly used antiemetic
  3. Indications
    Nausea and vomiting, Motion sickness, Enhance the effects of analgesics.
  4. Contrainindications
    Comatose patients, Pt's receiving large amounts of depressants. Known hypersensitivity to the drug.
  5. Precautions
    May impair mental and physical abilities; Care should be taken to prevent intra-arterial injection; EXTREMELY NECROTIC-Deep IM only; NEVER administer subcutaneously.
  6. Dosage and Administration
    • Standard dose is 12.5-25mg IV or IM for nausea and vomiting; in conjunction with analgesics is 25 mg PO;
    • For antihistamine effects; 12.5mg followed by 12.5mg IM
    • Peds: 0.05-0.1mg/kg IV or IM
Card Set
Promethazine (Phenegran)
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