Sodium Bicarbonate (NaHCO3)
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Reserved for late in cardiac arrest after pt has been adequatley ventilated; its use in cardiac arrest is questionable due the absence of proven effectivness and numerous adverse reactions.
Mechanism of Action
- Sodium Bicarbonate provides bicarbonate ion to buffer strong acids (such as latic acid and forms a week, volatile acid. This acid is degraded to carbon dioxide and water. The end produtcs are removed through the kidneys or lungs. Excessive administration can cause metabolic alkalosis whic is worse than the metabolic acidosis being treated
- Hydrogen Ion + Bicarbonate Ion <> Carbonic Acid <> Water+Carbon Dioxide
Severe acidosis; Cardiac arrest, after ventilation and other problems have been corrected; Tricyclic antidepressent overdose
There are no Contraindications when used in the treatment of severe acidosis
Dosage and Administration
(Adult and Pediatric) 1mEq/kg IV bolus then repeat @ 0.5mEq/kg IV q 10 minutes
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