Drugs 2.txt

Card Set Information

Author:
Anonymous
ID:
89079
Filename:
Drugs 2.txt
Updated:
2011-06-04 12:49:40
Tags:
Drugs Anti viral anti fungal steroids
Folders:

Description:
Anti-viral, anti-fungal, steroids
Show Answers:

Home > Flashcards > Print Preview

The flashcards below were created by user Anonymous on FreezingBlue Flashcards. What would you like to do?


  1. Types of corticosteroids:
    • Glucocorticoids
    • Mineralocorticoids
    • Androgens
  2. When the body is stressed what happens?
    • Release cytokines esp IL-1
    • causes increase in cortisol level
    • This mobilises bodys glycogen and fat stores
  3. FX of glucocorticoids x4:
    • HPA axis feedback
    • Anti-inflamm FX
    • Metabolic FX
    • Immunosuppressive FX
  4. Name 6 uses of steroids in dentistry:
    • 1.Ledermix, pulpal inflamm
    • 2.Oral ulceration
    • 3.Oral mucosal lesions eg.lichen planus
    • 4.Vesicullo bullous disorders
    • 5.Bells Palsy
    • 6.Temporal arteritis
  5. Steroids have differing levels of potency. Classify hydrocortisone and betamethasone:
    • Hydrocortisone mild
    • Betamethasone strongest, most potent
  6. What is a Corlan tablet?
    • Hydrocorticosone hemisuccinate 2.5mg
    • 1 tablet sucked 4 times/day.
    • Pts often done like putting the tablet next to the ulcer, painful.
  7. What is adcortyl A?
    • Triamcinalone acetonide in orabase
    • Discontinued
  8. What is betnasol mouthwash?
    • 500 MICROgrams betamethasone tablet dissolved in 5ml water
    • Rinse and hold next to ulcer 2mins
  9. What is Becotide?
    • Beclomethasone metered inhaler
    • Spray onto site 4 times a day.
    • 50/100/200 MICROgrams
  10. Dermovate cream?
    Clobetasol 0.05% cream
  11. Tacrolimus cream?
    0.1%
  12. Difflam mouthwash/spray?
    Benzydamine hydrochloride
  13. Systemic options for ulcers?
    • Prednisolone 20-40g daily for 5 days.
    • Reduce by 5mg every 2days.
    • Azathioprine 150mg daily
    • Others: colchicine, thalidomide, dapsone
  14. Any other METHODS to treat ulcers?
    • Intralesional injection
    • With 10mg/ml Triamcinalone acetonide
  15. Danger of Dapsone?
    Decrease in red blood cell count
  16. Principles of systemic steroids?
    • Lowest dose as possible
    • Shortest length of time
    • Take in morning
    • Caution withdrawing -Hypoadrenalism
  17. Who gets steroid cover?
    • More than 10mg Prednis daily, including if within the past 3 months
    • Double the dose 1hr before surgery and for 24hrs postop.
  18. Who carries a steroid card?
    Steroids >3 weeks
  19. Adrenal crisis symptoms:
    • N + V
    • Abdo pain
    • Low glucose
    • Increase K
    • Low Na
    • Dehydration
    • Hypotension
  20. Why get adrenal crisis?
    Adrenal suppression from long term supplements. Therefore decreased response to stress.
  21. Side FX streroids?
    • Weight gain
    • Susceptibility to infection
    • Hypertension
    • Precipitation/aggravate diabetes
    • Hyperglycaemia
    • Osteoporosis
    • Peptic ulceration
    • Cataracts
  22. Monitor what for a pt on steroids?
    • Weight
    • BP, electrolytes
    • Liver function
    • Glucose
    • Random cortisol
    • fbc
    • synACTHen
  23. Name 5 immunomodulatory drugs?
    • azathioprine
    • Colchicine
    • thalidomide
    • dapsone
    • tacrolimus
  24. Pts on Azathioprine need monitoring because?
    • Causes bone marrow suppression
    • Hepatotoxic
    • therefore take LFTs and FBC
    • Long term may predispose to neoplasms
  25. Antiviral drugs give 2 examples:
    • Aciclovir
    • Penciclovir
  26. Aciclovir doses?
    • Topical 5% cream FIVE times daily for 5-10 days
    • Systemic 200mg FIVE times a day PO or 400mg if immunocomp for 5 days
  27. Pencliclovir cream?
    1% every 2 hours
  28. Topical Antifungal names and doses
    • Nystatin pastilles 100,000 units QDS
    • Miconazole gel QDS
  29. Fluconazole dose and duration?
    50-100mg for 7-14days
  30. Itraconazole?
    100mg for 15days

What would you like to do?

Home > Flashcards > Print Preview