MAPRadiobio

Card Set Information

Author:
jakeschis
ID:
89253
Filename:
MAPRadiobio
Updated:
2011-06-05 12:56:24
Tags:
MAP Radiobiology
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Description:
MAP Final - Radiobiology
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  1. Key limitations in treating mass casualty
    • 1. bed capacity/availability
    • 2. burn and trauma care
    • 3. decontamination
    • 4. antidotes
  2. Ionizing Radiation types
    • alpha: doesnt go through uniforms
    • beta: internal contamination (GI, airways)
    • gamma/neutron: goes right through you
  3. Properties of Fallout
    • -reaches ground after first 24hrs
    • 7/10 rule: for every 7 hours, 10-fold increase in radiation risk
  4. Acute Radiation Syndrome
    • prodromal: nausea, vomiting, diarrhea, hypotension
    • -transient
    • -lethal dose if seen 30 min - hr
    • latent phase: symptom free
    • -shorter this phase, higher the likelyhood of death
    • **manifest illness phase: three dose-dependent subsyndromes - hematopeitic, GI, CV/CNS
    • recovery/death phase: -
  5. Hematopoeitic syndrome
    • -1.5-2.0Gy
    • -immunosupression
    • -pneumonia a major issue
    • -earliest test, best predictor of outcome
  6. GI Syndrome
    • -3-7 Gy
    • -intestinal mucosal barrier destruction
    • -fluid loss, electrolyte imbalance
    • -enteric flora enter blood
    • -faster reproducing cells, more affected by radiation; all result in fatalities
  7. Cardiovascular/CNS syndrome
    • -20-30Gy
    • -already dead, body just hasnt figured it out yet
    • -death in 1-3 days due to circulatory collapse
  8. Management
    • Step 1: limit exposure (shielding, distance, time)
    • Step 2: decon
    • Step 3: treat - life threatening trauma first (w/in first four hours = expectant )
    • then treat radiation effects - burns, drugs

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