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specific antidotes

  1. Acetominophen
    • N-acetylcystein
    • -donate sulfhydryl groups
    • -acts as glutathione substitute, bind toxic metabolite
  2. Salicylates
    NaHCO3 dialysis (alkalinize urine)
  3. Amphetamines
    • NH4Cl
    • (acidify urine)
  4. AchE inhibitors, Organophosphates
    Atropine + Pralidoxine
  5. Antimuscarinic
    Anticholinergic
    (ex) Atropine
    Physostigmine
  6. Beta blockers
    Glucagon
  7. Digitalis
    • stop digitalis
    • normalize K+
    • Lidocaine
    • anti-digitalis Fab fragments
    • Mg+2
  8. Fe
    Deferoxamine
  9. Lead
    • CaEDTA, Dimercaprol
    • succimer
    • penicillamine
  10. Mercury, Arsenic, Gold
    • Dimercaprol
    • Succimer
  11. Copper, Arsenic, Gold
    Penicillamine
  12. Cyanide
    • Amyl nitrite
    • Hydroxocobalamin
    • Thiosulfate
  13. Methemoglobin
    • Methylene blue
    • Vit C
  14. CO
    100% O2, hyperbaric O2
  15. Methanol, ethylene glycol (oxalate)
    • ethanol
    • Fomepizole
  16. Opioids
    • Naloxone
    • Naltrexone
  17. BDZs
    Flumazenil
  18. TCA
    NaHCO3 (plasma alkalinize)
  19. Heparin
    Protamine
  20. Warfarin
    • Vit K
    • FFP
  21. tPA, Streptokinase
    Aminocaproic acid
  22. Theophylline
    beta blocker
Author
bshin
ID
89410
Card Set
specific antidotes
Description
specific antidotes
Updated

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