specific antidotes

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Acetominophen
- N-acetylcystein
- -donate sulfhydryl groups
- -acts as glutathione substitute, bind toxic metabolite
Salicylates

NaHCO3 dialysis (alkalinize urine)
Amphetamines
- NH4Cl
- (acidify urine)
AchE inhibitors, Organophosphates

Atropine + Pralidoxine
Antimuscarinic
Anticholinergic
(ex) Atropine

Physostigmine
Beta blockers

Glucagon
Digitalis
- stop digitalis
- normalize K+
- Lidocaine
- anti-digitalis Fab fragments
- Mg+2
Fe

Deferoxamine
Lead
- CaEDTA, Dimercaprol
- succimer
- penicillamine
Mercury, Arsenic, Gold
- Dimercaprol
- Succimer
Copper, Arsenic, Gold

Penicillamine
Cyanide
- Amyl nitrite
- Hydroxocobalamin
- Thiosulfate
Methemoglobin
- Methylene blue
- Vit C
CO

100% O2, hyperbaric O2
Methanol, ethylene glycol (oxalate)
- ethanol
- Fomepizole
Opioids
- Naloxone
- Naltrexone
BDZs

Flumazenil
TCA

NaHCO3 (plasma alkalinize)
Heparin

Protamine
Warfarin
- Vit K
- FFP
tPA, Streptokinase

Aminocaproic acid
Theophylline

beta blocker