SFOS 68

• Adenohypophysis (from oral ectoderm - Rathke's pouch)
• Neurohypophysis (from diencepthalon)

• Controls activity of other endocrine glands
• Secretes hormones

• Somatotrophs - growth hormone
• Mammotrophs - prolactin
• Thyrotrophs - thyroid stimulating hormone
• Gonadotrophs - LH or FSH
• Corticotrophs - corticotropin

• Somatotrophs
• Mammotrophs

• Thyrotrophs
• Gonadotrophs
• Corticotrophs

• Stimulates somatomedin production
• Necessary for normal growth

Initiates and maintains milk production

• Stimulates synthesis and release of thyroid hormone
• Proliferation of thyroid cells

• Females - used for ovarian follicular maturation
• Males - regulates sperm production

• Females - ovarian follicle maturation and ovulation
• Males - stimulates androgen production by Leydig cells of testes

Stimulates synth and release of glucocorticoids by adrenal cortex

• Hypofunction of gonads, adrenal cortex, thyroid
• Dwarfism

Melanocyte-stimulating hormone (no function in humans)

• Natural opiate like effect
• Endorphins
• Enkephalins
• Dynorphins

Axons and endings of neurosecretory neurons from supraoptic and paraventricular nuclei of the hypothalamus

Support cells of the Pars Nervosa

• Oxytocin - contraction of uterine smooth muscle and myoepithelial cells of lactating breast
• ADH - stimulates increased water reabsoption

ADH

• Neural control of circadian information
• Produces melatonin (influences gonads, other endocrine glands)

• High secretion at night, low during day
• Inhibited by light