Intro to pharm

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  1. The study of drugs, when administered to a living organism, it produces a change in function
  2. The study of the processes each drug undergoes
  3. process of pharmacokinetics
    • ADME:
    • Absorption
    • Distribution
    • Metabolism
    • Excretion
  4. The study of the mechansim of action of a drug
  5. The study of how drugs work in the body
  6. the study of how drugs treat a disease or condition
  7. the act of preparing and dispensing of medication by pharmacists and their staff
  8. the study of the poisonous effects drugs have in the body
  9. two pharmacology principles
    • Drugs do not create function; they modify existing fxns of the body
    • no drug has a single action
  10. effects of drugs
    • therapeutic effect
    • side effect
    • toxic effect
    • lethal effect
    • allergic reaction
  11. The desired effect of the drug
    therapeutic effect
  12. the undesireable effect of a drug produced in addition to the desired effect upon administration of the drug
    side effect
  13. a side effect that can be harmful or life threatening to the body
    toxic effect
  14. an effect that kills
    lethal effect
  15. an altered state of reaction to a drug, resulting from previous sensitizing exposure and the development of an immunologic response
    allergic reaction
  16. symptoms of an allergic reaction
    • decreased breathing
    • decrease in blood pressure
    • weakness
    • n/v
    • hives-redness
    • cardiac arrest
    • death
  17. the description or wording of how a drug works in the body
    Mechanism of Action (MOA)
  18. the location within the body where the drug exerts its therapeutic effect.
    site of action
  19. are all sites of action known?
  20. the location on the site of action where the drug binds to a cell in order to cause an effect
    receptor site
  21. the drug and the receptor site must have the correct configuration to produce a desirable effect
    lock and key
  22. a drug that binds to a specific receptor site and produces a therapeutic effect or action
    agonist drug
  23. a drug that competes with the agonist or neurotransmitter (NT) for the receptor site causing the agonist unable to produce a desireable effect.
    antagonist drug (blocker)
  24. When a perons is on a drug for a long time and then is without, the perosn starts to feel symptoms: tremors, abdominal cramps, sweat, and convulsions
    physical dependence
  25. When a person has becoem addicted to a particular drug and they are left without, the perosn starts to feel anxiety, tension, and stress
    psychological dependence
  26. A method of classifying drugs according to documented problems in pregnancy
    Pregnancy safety categories
  27. What are the pregnancy safety categories
    • A: do not show an increased risk of birth defects or fetal abnormalities
    • B:Animal studies have not revealed an increased risk of birth defects or fetal abnormalities, but there are not adequate studies in pregnant women OR animal studies have shown an effect but adequate controlled trials in pregnant women have not shown an increased risk of birth defects or fetal abnormalities.
    • C:Animal studies have shown an adverse effect and there are no studies in pregnant women OR no animal studies have been done and there are no adequate controlled trials in pregnant women.
    • D:Adequate controlled trials or observational studies in pregnant women have proven an increased risk of birth defects or fetal abnormalities. However, benefits of therapy may outweigh the risks involved.
    • X:Adequate controlled trials or observational studies in pregnant women and/or animals have proven an increased risk of birth defects or fetal abnormalities. These medications are contraindicated during pregnancy.
  28. When the combined effect of 2 drugs each producing the same biological response by the same MOA, is = to the sum of their individual effects
    additive effects
  29. when 2 drugs having the same biological response, NOT by the same MOA, are given together; the effect is GREATER thatn the sum of each drug if given alone
    synergistic effect
  30. Able to disturb the growth and development of an embryo or fetus
  31. Introduced into or occurring in the space under the arachnoid membrane which
    covers the brain and spinal cord.
  32. The degree to which a fluid resists flow under an applied force, measured by the
    tangential friction force per unit area divided by the velocity gradient under
    conditions of streamline flow
  33. ac
    before meals
  34. pc
    after meals
  35. stat
  36. po
    by mouth
  37. prn
    as needed
  38. q
  39. qd
  40. bid
    twice daily
  41. tid
    three times daily
  42. qid
    four times daily
  43. hs
    hours of sleep
  44. ou
    each eye
  45. au
    each ear
  46. as
    left ear
  47. od
    right eye
  48. ad
    right ear
  49. os
    left eye
  50. adverse reaction
  51. iatrogenic response
Card Set:
Intro to pharm
2011-06-08 03:06:41

pharm 1
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