Card Set Information
what kind of disease is Kawasaki?
small-medium vessel systemic vasculitis
why is Kawasaki's disease an important diagnosis to make?
as aneurysms of coronary arteries are important complication!
what % of cases are affected by coronary artery aneurysm?
what age group goes KD affect?
6 month - 4 year
peak 1 year
who is KD more common in?
what is cause of KD?
maybe bacterial toxin acting as superantigen
how is diagnosis of KD made?
based on clinical findings
need 5 out of 6 of:
1. fever for 5 days or more
3. bilateral conjunctival injection (non purulent)
: red, dry, cracked, strawberry tongue
- red palms and soles
- indurative oedema of handset
- peeling of skin on hands and feet
6. cervical lymphadenopathy
: can be unilateral, non purulent
what is differential diagnosis of KD?
which Ix need to be done in suspected KD?
Throat swab, ASOT
Blood culture, viral titre
why is echo done?
detect coronary artery aneurysm
what is the most effective Rx of KD? and when?
IvIg 2g/kg within first 10 days
reduces coronary artery aneurysm
apart from IvIg what else is given and why? and dose?
aspirin to reduce thrombosis risk
first at high anti-inflammatory dose until fever subsides
then low anti-platelet dose