Diphenhydramine (Benadryl)

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  1. Class
    Anithistamine
  2. Description
    Diphenhydramine blocks histamine release, thereby reducing bronchoconstriction, vasodilation, edema and capillary cell leakage.
  3. Mechanism of Action
    Histamine blocker, has some slight sedative effects.
  4. Onset of Action
    • Onset: varies
    • Peak: varies
    • Duration: varies
    • Half-Life: varies
  5. Indications
    Anaphylaxis-not used as first line agent, use epi, allergic reaction, dystonic reaction due to phenothiazine's.
  6. Contraindications
    Asthma (use precaution because it's not always contraindication, nursing mother)
  7. Precautions
    None when used in emergency
  8. Side Effects
    Blurred vision dries bronchial secretions, headache, and palpitations.
  9. Adult Dose
    25-50mg
  10. Pedi-Dose
    1-2mg/kg
  11. Max Dose
    50mg
  12. Routes of Administration
    slow IV push, Deep IM
  13. How supplied
    prefilled syringes
Author
ID
89930
Card Set
Diphenhydramine (Benadryl)
Description
Paramedic Drugs
Updated
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