Antibacterial Choices DOC

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Anonymous
ID:
9040
Filename:
Antibacterial Choices DOC
Updated:
2010-03-03 22:06:55
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ABX
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Description:
ABX DRUGS AND BUGS
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  1. Staphlococcus epidermidis or aureus
    DOC:
    • Naficillin
    • Oxacillin
    • (Isoxazolpenicillin)
  2. MRSA or MRSE
    DOC:
    Vancomycin +- gentamicin or +- rifampin
  3. Streptococcus Pyogenes
    Group A C and G
    DOC:
    Penicillin or amoxicillin

    Alternative: Erythromycin (macrolide) or clindamycin or first gen ceph

    note:clarithromycin is not recommended in pregnant women
  4. Streptococcus agalactiae (group B)
    DOC:
    Penicillin or Ampicillin
  5. Streptococcus viridans
    DOC
    • Penicillin +- gentamicin
    • resistance may be an issue

    Alt: cephalosporin or vancomycin
  6. S. pneumoniae with PCN-susceptability of MIC<0.1mcg/ml
    Penicillin or amoxicillin

    alt: macrolide, ceph, TMP/SMX

    note: 15% of cases are highly resistant
  7. S. pneumoniae with PCN-susceptability of MIC 0.1-1mcg/ml
    DOC: penicillin G IV

    ceftriaxone (3rd)
  8. S. pneumoniae with PCN-susceptability of MIC>2mcg/ml
    meningitis: vancomycin + ceftriaxone or cefotaxime +- rifampin

    other infections: vanco +ceftriaxone OR levofloxacin, moxifloxicin (quinolones)
  9. Entercoccus faecalis
    blood/skin and soft tissue
    PCN G or amp + gentamicin

    alt: Vancomycin +- gentamicin
  10. Entercoccus faecalis
    UTI uncolmplicated
    Ampicillin or amoxicillin

    or Nitrofurantoin
  11. Enteroccus faecium
    Vanco +- gent
  12. Listeria monocytogenes
    gram + bacilli
    • Ampicillin +- gentamicin
    • or TMP/SMZ
  13. moraxella catarrhalis

    g- cocci
    cefuroxine or fluoroquinolone

    not greater than 80% make B-lactamase
  14. Neisseria gonorrhoeae
    • Ceftriaxone
    • cefixime
    • (3rd generation)
  15. Neisseria meningitidis
    • DOC:
    • PCN

    Alt: cefotaxime, ceftriaxone

    • chloramphenocol (mis)
    • sulfonamide
    • fluoroquinolone
  16. gram negative
    bacilli
    enterobacteriaceae
    next few foo
  17. E. Coli
    Cefepime (4th gen) or 3rd generation ceph: (cefotaxime, ceftriaxone, ceftazidime)
  18. K. pneumoniae
    Cefepime (4th gen) or 3rd generation ceph: (cefotaxime, ceftriaxone, ceftazidime)
  19. P. mirabilis (indole-)
    Ampicillin

    alt: beta lactamse combo
  20. P. Vulgaris (indole +)
    Cefepime (4th gen) or 3rd generation ceph: (cefotaxime, ceftriaxone, ceftazidime)
  21. Providencia stuartii
    Cefepime (4th gen) or 3rd generation ceph: (cefotaxime, ceftriaxone, ceftazidime)
  22. Enterobacter spp.
    Imipenem or meropenem (carbapenems)
  23. Serratia marcescens
    Imipenem or meropenem
  24. other gram - bacilli----
  25. H. influenzae
    meningitis, epiglottis, arthritis and serious infections
    Cefotaxime or ceftriaxone

    note: 30% of strains create B lactamase
  26. H. Influenzae
    URI and bronchitis
    TMP/SMZ
  27. pseudomonas aeruginosa
    • UTI: fluoroquinolone
    • other infection: carboxy or ureidopenicillin

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