SFOS 75

The flashcards below were created by user zf2010 on FreezingBlue Flashcards.

Cretinism
- Hypothyroidism from birth
- Intellectual and developmental impairment
Myxedema

Severe hypothyroidism with generalized edema
Lymphocytic (Hashimoto's) thyroiditis

Cytotoxic antibodies attack thryoid follicular cells
What mediates the formation of a goiter?

Increased TSH levels in response to chronic low thyroid hormone levels
What are the pituitary causes of hypothyroidism?
- Pituitary tumor
- Sheehan's syndrome (postpartum)
- Autoimmune hypohysitis
TSH levels in:

1. Primary thyroid disease
2. Pituitary or hypothalamic disease
- 1. Increased
- 2. Low or undetectable
Thyrotoxicosis
- Tissue is exposed to excess thyroid hormone
- Can be caused by hyperthyroidism
Grave's disease
- Hyperthyroidism from diffuse toxic goiter
- Caused by TSH receptor-stimulating autoantibodies
- Continuous thyroid hormone synthesis
Treatment of thyrotoxicosis
- Antithyroid agents - block hormone synthesis
- Radioactive iodine therapy (resulting hypothyroidism)
- Subtotal thyroidectomy (resulting hypoparathyroidism)
Causes of hyperthyroidism
- Grave's disease
- TSH-mediated hyperthyroidism (pituitary adenoma)
- Trophoblastic thyrotoxicosis (HCG stimualtes thyroid production)
- Iodine-induced thyotoxicosis (excess iodine)