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Which hormone is dominant in which menstrual phase?
- Follicular - estrogen
- Luteal - progesterone
What stimulates granulosa cell proliferation?
What triggers the positive feedback of estrogen?
The profile of increasing blood estrogen during the follicular phase
What transports steroid hormones in blood?
- sex hormone binding globulin
- cortisol binding globulin
Functions of the cervix
- Raptid transport of sperm
- Colonization of sperm in cervical crypts, slow release
Describe Sprem capacitation
Acrosome reaction - sperm interacts with zona pellucida and digests way to oocyte
What are the cell types of the blastocyst?
- Inner cell mass - fetus
What are the roles of HCG?
- Maintaining the corpus luteum progesterone secretion
- Stimulating testosterone secretion by the fetal testis
- Its presence is the earliest definitive sign of pregnancy
What are the roles of Human Placental Lactogen?
- Mobilization of maternal fat stores
- Peripheral insulin resistance in the mother (gestational hyperglycemia)
- Promotes breast development
What are the roles of Progesterone in pregnancy?
- Inhibits the hypothalamus from initiating another menstrual cycle
- Maintains vascular bed
- Inhibits uterine smooth muscles despite their stimulation by estrogen
What are the roles of Estrogen in pregnancy?
- Development and growth of uterus
- Promote breast development
- Soften elastic tissues
- Stimulates clotting factor production
What are the major effects of labor?
- Progesterone decline
- Sustained high estrogen levels
- Prostaglandin formation
- Increased oxytocin receptors
- Relaxin and oxytocin secretion
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