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What is the path of individual sperm?
What are the functions of Sertoli cells?
Maintaining high local androgen level
Secrete inhibin (feedback loop for FSH)
What is the process of sperm maturation?
Primary spermatocytes (Meiosis I)
Secondary spermatocytes (Meiosis II)
Where do sperm gain motility?
What is the function of Leydig cells?
What controls them?
Regulated by LH (ICSH)
Inflammation of the epididymis
Common cause of infertility
Usually due to gonorrhea
Accessory sex glands
Seminal vesicle - secretion high in fructose controlled by testosterone
Describe mechanism of erection
Parasympathetic release of ACh
Causes endothelium to release nitric oxide
NO promotes increased cGMP
Promotes smooth muscle relaxation/increased blood flow to corpora cavernosa
What is the mechanism of action of Viagra?
Blocks enzyme that breaks down cGMP
What produces Mullerian inhibiting substance?
Benign prostatic hypertrophy
Nodules in mucosal and submucosal regions
PSA and prostatic cancer
Prostate Specific Antigen - increased levels in blood if cancer present
Male Reproduction System