Unit 2 Drug Cards

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face12
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91151
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Unit 2 Drug Cards
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2011-06-21 14:49:51
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Santana ACC Pharmacology
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This is a list of all the Unit 2 Drug Cards
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  1. Acetylcholine (Miochol-E)
    • Class: Direct-Acting Cholinergic Agonist
    • MOA: Directly stimulates muscarinic and nicotinic receptors
    • Therapeutically of little importance except topically in treatment of glaucoma
    • Side Effects: Diarrhea, Diaphoresis(sweating), Miosis, Bronchospasm, Urinary urgency, Salivation
  2. Bethanechol(Urecholine)
    Class Direct_Acting Cholinergic Agonist

    MOA: Directly stimulates muscurainic receptrs on the gastrointestinal and urinary smooth muscle but has a stronger structure that makes it last longer in the body.

    Therapeutic: Reflux esophagitis & urinary retention (post operative, post partum)

    Side Effects: Diarrhea, Diaphoresis(sweating), Miosis, Bronchospasm, Urinary urgency, Salivation
  3. Pilocarpine (Isopto Carpine)
    • Class: Direct-Acting Cholinergic Agonist
    • MOA:directly stimulates muscarinic receptors

    Therapeutic use are primarily in ophthalmologySide Effects: Diarrhea, Diaphoresis(sweating), Miosis, Bronchospasm, Urinary urgency, Salivation


    *Drug of choice in emergency lowering of intraocular pressure (glaucoma)
  4. Neostigmine(Prostigmin) & Physostigmine(Generics)
    • Class: Indirect-Acting Cholinergic Agonist
    • MOA: Stimulate muscarinic and nicotinic sites
    • Therapeutic Uses: Stimulation of the bladder and GI tract. Antidotes for overdoses of anticholinergic drugs like Atropine, antipsychotic drugs, antidepressants, tubocurarine. Treatment of Myasthenia gravis(deterioration of Nmreceptors at the neuromuscular

    Side Effects: Diarrhea, Diaphoresis(sweating), Miosis, Bronchospasm, Urinary urgency, Salivation
  5. Atropine
    • MOA: High affinity for muscarinic receptors
    • Therapeutic Uses: Mydiratic effects, antispasmodic effects(relaxes GI and bladder), antisecretory effects before surgery and in asthma or COPD, bronchdilating effects and an antidote for cholinergic agonists
    • Side effects: blurred vision, dry mouth, constipation, urinary retention, drowsiness, tachycardia
  6. 1)Tubocurarine(generics),
    2)atracurium(Tracrium*)
    3)Rocuronium (Zemuron*)
    • Class: Neurumuscular Blocking Drugs (somatic)
    • MOA Block cholinergictransmission betwenen moter ner endings and nicotinic receptors
    • Therapeutic Uses: helpful (adjuvent) drug used in surgery to relax muscle
  7. Epinephrine
    • Class: Direct acting adrenergic agonist
    • MOA: interacts with both a and b receptors
    • Therapeutic Uses: At low doses vasodilation b predominates. at high doses vasoconstriction a is strongest...Acute asthma
    • Side affects:cardiac arrythmias headace hyperactivity
  8. Noraepinephrine
    • Class: Directacting adrenergic agonists
    • MOA:binds with a1, a2, b1
    • Therapeutic uses: treatment of shock
    • Side affects:cardiac arrythmias headace hyperactivity
  9. Isoproterenol
    • Class: Direct acting adrenergic agonist
    • MOA: interacts with both b1 and b2 receptors
    • Therapeutic Uses: As bronchodilator in asthma & as cardiac stimulant
    • Side affects:cardiac arrythmias headace hyperactivity
  10. Dopamine
    • Class: Direct acting adrenergic agonist
    • MOA: Interacts with b1/dopaminergic
    • Therapeutic uses: treatment of shock
    • Side affects:cardiac arrythmias headace hyperactivity
  11. Dobutamine
    • Class: Direct acting adrenergic
    • MOA: acts on b1
    • Therapeutic Uses: treatment of congestive heart failure
    • Side affects:cardiac arrythmias headace hyperactivity
  12. Phenylephrine
    • Class: Directs acting adrenergic
    • MOA: acts on a1
    • Therapeutic Uses: nasal decongestant

    Side affects:cardiac arrythmias headace hyperactivity
  13. Metaproterenol
    • Class: Direct Acting adrenergic agonist
    • MOA: stimulates b2>b1 receptors
    • Therapeutic Uses: treatment of bronchospasm
    • Side affects:cardiac arrythmias headace hyperactivity
  14. Terbutaline and Albuterol
    • Class: Direct acting adrenergi agonist
    • MOA: stimulates B2 receptors
    • Therapeutic Uses: treatment of bronchospasma and premature labor
    • Side affects:cardiac arrythmias headace hyperactivity
  15. Ephedrine
    • Class: Mixed action adrenergic agonists
    • MOA: releases stored noraepinephrine from nerve endings. Directly stimulates both a and b receptors and CNS.
    • Therapeutic uses: treatment of asthma
    • Side affects:cardiac arrythmias headace hyperactivity
  16. Phentolamine(Regitine)
    • Class: adrenergic antagonists
    • MOA: blocks a1 and a1
    • Therapeutic Uses: used in pheochromocytoma(adrenal tumors)
    • Side affects: Hypotension, Bradycardia
  17. Terazosin(Hytrin) & Doxazosin(cardura)
    • Class: adrengic antagonists
    • MOA: Blocks a1
    • Therapeutic uses:for benign prostatic hypertrophy
    • Side affects: Hypotension, Bradycardia
  18. Tamsulosin (Flomax)
    • Class: adrenergic antagonist
    • MOA: blocks a1A receptor
    • Therapeutic uses: helps urine flow in bladder
    • Side affects: Hypotension, Bradycardia
  19. Propranolol(inderal)
    • Class: adrenergic antagonist
    • MOA: Competitively blocks b1 and b2 receptors
    • Therapeutic uses: Hypertension, angina pectoris
    • Side effects: Hypotension, bradycardia
  20. Atenolol(tenormin) & Metoprolol (lopressor)
    • Class: adrenergic antagonist
    • MOA: competitively blocks b1 receptors(cardioselective)
    • Therapeutic uses: hypertension
    • Side effects: Hypotension, bradycardia
  21. Pindolol (Visken)
    • Class: adrenergic partial agonist as blockers
    • MOA: weakly stimulates both b1 and b2 receptors, but inhibit stimulation by epinephrine and norepinephrine, reesulting in a much more diminished effect.
    • Therapeutic uses: hypertension
    • Side effects: Hypotension, bradycardia
  22. Labetolol(Normodyne)
    • Class: adrenergica partial agonist as a blocker
    • MOA: blocks b1,b2 receptors and a1 receptors
    • Therapeutic uses: hypertension
    • Side effects: hypotension, bradycardia
  23. cromolyn(Intal)
    • Class: Direct acting adrenergic agonists with B2 activity
    • MOA: inhibits the release of histamine from mast cells
    • Therapeutic uses: Mild asthma
    • Side effect
  24. Ipratropium(atrovent)
    • Class: Cholinergic antagonists
    • MOA: Blocks muscurinic receptors
    • TherapeuticUses: Emphysema/asthma
    • SideEffects: cough, dizziness, drymouth
  25. metroprolol(lopressor)
    • Class: beta adrenergic antagonist
    • MOA: blocks beta receptors on sympathethic nerves
    • Therapeutic Uses: reduces force of contraction of the heart therby lowering drug pressure
  26. salmeterol(serevent)
    • Class: Direct acting adrenergic agonists with b2 activity
    • MOA: it is a broncho dilater that focuses on b2
    • Therapuetic uses: asthma reatment
  27. Beclemethasone(Beclovent), Triamcinolone(Azmacort), Flunisolide
    • Class: CORTICOSTEROIDS
    • MOA:decrease number of cells involved in airway inflammation macrophages and basophils
    • Therapeutic uses: allerginic rhinitis asthma
    • Side effects:burning itching irritation
  28. Theoplylline(aminophylline)
    • Class:direct acting agonists b2 activity
    • MOA: relaxes smooth muscle of broinchioles
    • Therapeutic uses: Asthma treatment
    • Side effects: burining itching irritation

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