Rate determing enzymes

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Author:
nhpatel
ID:
93244
Filename:
Rate determing enzymes
Updated:
2011-07-07 00:18:59
Tags:
enzymes
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Description:
Rate-determing enzymes of metabolic processes
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  1. Glyolysis
    Phosphofructokinase-1 (PFK-1)
  2. Gluconeogenesis
    Fructose-1,6-bisphosphatase
  3. TCA cycle
    Isocitrate Dehydrogenase
  4. Glycogen synthesis
    Glycogen synthase
  5. Glycogenolysis
    Glycogen phosphorylase
  6. HMP shunt
    Glucose-6-phosphate dehydrogenase (G6PD)
  7. De novo pyrimidine synthesis
    • Carbamoyl phosphate synthetase II
    • Get nitrogen from glutamine (cytosol)
  8. De novo purine synthesis
    Glutamine-PRPP amidotransferase
  9. Urea Cycle
    • Carbamoyl phosphate sythetase I
    • Get nitrogen from ammonium (mitochondria)
  10. Fatty acid synthesis
    Acetyl-CoA carboxylase (ACC)
  11. Fatty acid oxidation (degradation)
    Carnitine acyltransferase I
  12. Ketogenesis
    HMG-CoA synthase
  13. Cholesterol synthesis
    HMG-CoA reductase
  14. Heme synthesis
    Aminolevulonate synthase
  15. Bioacid Synthesis
    7-alpha-hydroxylase synthase

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