Side Effects

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Author:
AstephZ
ID:
95113
Filename:
Side Effects
Updated:
2011-07-25 01:25:55
Tags:
Drugs
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Description:
Common Drug Side Effects
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  1. Pt presents with:
    cough, rash, proteinuria, angioedema, taste changes, teratogenic effects
    ACEIs
  2. Pt presents with:

    ataxia, livedo reticularis (lace-like purplish discoloration of the lower extremities)
    Amantadine
  3. Pt presents acutely with:

    AV block, hypotension, bradycardia
    Amiodarone
  4. Pt presents with chronic complaints of:

    pulmonary fibrosis, peripheral deposition leading to bluish discoloration, arrhythmias, hypo-hyperthyroidism, corneal deposition
    Amiodarone
  5. Pt presents with:

    Fevers/rigors, nephrotoxicity, bone marrow suppression, anemia
    Amphotericin
  6. HIV patient presents with

    Thrombocytopenia, megaloblastic anemia
    Zidovudine (AZT)
  7. Hypercholesterolemic pt presents with:

    GI upset, malabsorption of vitamins and medications
    • Bile acid resins:
    • Cholestyramine
    • Colestipol
    • Colesevelam
  8. Pt with arrhythmias presents with:

    peripherial edema, flushing, constipation, cardiac depression
    • CCBs:
    • Dihydrophyridines - nifedipine, felodipine, amlodipine

    Nondihydropyridines - diltiazem, verapamil
  9. Bipolar patient presents with:

    agranulocytosis, aplastic anemia, liver toxicity

    drug can also induce P-450
    carbamazepine
  10. Antibiotic that presents with:

    gray baby syndrome, aplastic anemia, and hemolysis in G6PD deficient patients
    Chloramphenicol
  11. Chemotherapeutic agent causes:

    nephrotoxicity, acoustic nerve damage
    cisplatin
  12. Pt with hx of HTN presents with:

    dry mouth; severe rebound headache and HTN
    clonidine
  13. Atypical antipsychotic known for:

    agranulocytosis
    Clozapine
  14. Immunosuppression agent that causes pts to have:

    mania, hyperglycemia, bone mineral loss, thinning of skin, easy bruising, myopathy, cataracts (chronic)
    corticosteroids
  15. Chemotherapeutic agent that causes:

    myelosuppression, hemorrhagic cystitis
    cyclophosphamide
  16. Antiarrhythmic that causes:

    GI disturbances, yellow visual changes, arrhythmias (junctional tachycardia or SVT)
    digoxin
  17. Chemotherapeutic agent known for:

    cardiotoxicity (cardiomyopathy)
    doxorubicin
  18. Used to treat methanol or ethylene glycol toxicity causes:

    renal dysfunction, CNS depression
    Ethyl alcohol
  19. ATBX that causes:

    cartilage damage in children; achilles tendon rupture in adults
    • Fluoroquinolones:
    • ciprofloxacin
    • levofloxacin
    • ofloxacin
  20. HTN pt presents with:

    ototoxicity, hypokalemia, nephritis, gout
    Furosemide
  21. Pt with hypercholesteremia presents with:

    myositis, reversible increase in LFTs, cholelithiasis, GI upset
    gemfibrozil
  22. Anesthetized pt with:

    malignant hyperthermia, hepatotoxicity
    halothane
  23. HTN pt with:
    Hypokalemia
    Hyponatremia
    Hyperuricemia
    Hyperglycemia
    Hypercalcemia
    HCTZ
  24. Hyperlipidemic pt presents with:

    increase LFTs, myositis, warfarin potentiation
    • HMG-CoA reductase inhibitors
    • simvastatin
    • atorvastatin
    • lovastatin
    • pravastatin
    • rosuvastatin
  25. SLE patient with malaria presents with:

    retinopathy
    hydroxycholoroquine
  26. Patient with malaria presents with:

    peripheral neuropathy, hepatotoxicity, inhibition of P-450, seizures with overdoes, hemolysis in G6PD deficiency
    INH

    prophylaxis w/ pyridoxine (vit B6)
  27. Depressed patient presents with:

    hypertensive tyramine reaction, serotonin syndrome with meperidine
    • MAOIs:
    • phenelzine
    • tranylcypromine
    • selegiline
  28. Other than metabolic acidosis, overdose of this can cause:

    blindness
    methanol
  29. Immunosuppressive agent that causes:

    hepatic fibrosis, pneumonitis, anemia
    methotrexate
  30. Alpha2 agonist used for HTn that can cause:

    + Coombs' test, drug-induced SLE, blood dyscrasias,
    Methyldopa
  31. Pt with hx of STD presents with:

    disulfiram reaction, vestibular dysfunction, metallic taste
    metronidazole
  32. Hyperlipidemic pt presents with

    Skin flushing, paresthesias, pruritis, GI upset, and increased LFTs
    Niacin
  33. Pt with acute MI develops:

    hypotension, tachycardia, headache, tolerance
    Nitroglycerin
  34. Used in patients with RA, Wilson's disease, arsenic poisoning, lead toxicity, primary biliary cirrhosis causes

    drug-induced SLE
    penicillamine
  35. HTN agent with

    first dose hypotension
    prazosin
  36. Antiarrhythmic agent used for ventricular arrhythmias and SVTs presents with

    drug-induced SLE
    procainamide
  37. Pt with Grave's disease presents with

    agranulocytosis, aplastic anemia
    propylthiouracil
  38. Antiarrhythmic and malarial agent used to treat atrial flutter, afib and ventricular arrhythmias that presents with;

    headache, tinnitus, thrombocytopenia, torsades de pointes, induces P-450, increase risk of digoxin toxicity, and drug induced SLE
    Quinidine
  39. HTN patient presents with

    depression
    reserpine
  40. Epileptic pt with:

    nystagmus, diplopia, ataxia, arrhytmia, gingival hyperplasia, hirsutism, teratogenic effects
    Phenytoin
  41. Pt with hx of stroke presents with:

    fever, hyperventilation with respiratory alkalosis and metabolic acidosis, dehydration, diaphoresis, hemorrhagic gastritis
    • Salicylates:
    • ASA
  42. Pt with hx of depression presents with:

    anxiety, sexual dysfunction, serotonin syndrome if taken with MAOIs
    • SSRIs:
    • fluoxetine,
    • sertraline
    • paroxetine
    • citalopram
    • fluvoxamine
  43. Pt with neuromusclar blockade presents with:

    malignant hyperthermia, hyperkalemia
    succinylcholine
  44. Pt with hx of depression:

    sedation, coma, anticholinergic effects, seizures and arrhythmias
    • TCAs:
    • nortriptyline
    • desipramine
    • amitriptyline
    • imipramine
  45. ATBX that causes:

    tooth discoloration, photosensitivity, Fanconi's syndrome, GI distress
    • Tetracyclines:
    • demeclocycline
    • doxycycline
    • minocycline
    • tetracycline
  46. ATBX that causes:

    megaloblastic anemia, leukopenia, granulocytopenia
    Trimethoprim
  47. Bipolar or psychotic patient with:

    neural tube defects, and fata hepatotoxicity
    Valproic acid
  48. ATBX that causes:

    nephrotoxicity, ototoxicity, and "red man syndrome"
    Vancomycin
  49. Chemotherapeutic agent that causes:

    severe myelosuppression
    Vinblastine
  50. Chemotherapeutic agent that causes:

    peripheral neuropathy, paralytic ileus
    vincristine

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