shosh: resp drugs

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Author:
shosh114
ID:
95316
Filename:
shosh: resp drugs
Updated:
2011-07-26 18:13:44
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  1. Isoproterenol
    • Beta 2 agonist, relaxes bronchiolar smooth muscle
    • Activation of beta 1 receptors causes tachycardia
  2. Albuterol
    • Specific beta 2 agonist
    • Use for acute asthma attacks
  3. Salmeterol
    Long acting beta 2 agonist, use for prophylaxis against asthma attacks
  4. Theophylline
    • A methylxanthine, inhibits phosphodiesterases which increases cAMP concentration
    • Use for asthma
    • Cardiotoxic
    • Blocks action of adenosine
  5. Ipratropium
    • A muscarinic antagonist, causes competitive blockade of muscarinic receptors, which prevents bronchoconstriction
    • Use for asthma and COPD
  6. Cromolyn
    • Prevents release of mast cell mediators
    • Use for prophylaxis of asthma
  7. Beclomethasone, prednisone
    • Steroids. Inhibit cytokine synthesis and NFkappa-B, which induces production of inflammatory agents
    • First line treatment for chronic asthma
  8. Flunisolide
    Aerosolized steroids, use for asthma
  9. Zileuton
    • Inhibits the lipoxegenase pathway, blocks leukotriene synthesis
    • Use for asthma
  10. Zafirlukast, montelukast
    • Block leukotriene receptors
    • Use for aspirin-induced asthma
  11. N-acetylcysteine
    • Sulfhydryl group donor, breaks up mucus plugs in CF patients
    • Also used for acetaminophen toxicity
  12. Bosentan
    Competetive antagonist of endothelin receptors, used to treat pulmonary hypertension

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